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(6-)ε-​Aminocaproic acid

CAS# 60-32-2

(6-)ε-​Aminocaproic acid

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(6-)ε-​Aminocaproic acid: 5mg $23 In Stock
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Chemical structure

(6-)ε-​Aminocaproic acid

3D structure

Chemical Properties of (6-)ε-​Aminocaproic acid

Cas No. 60-32-2 SDF Download SDF
PubChem ID 564 Appearance Powder
Formula C6H13NO2 M.Wt 131.17
Type of Compound N/A Storage Desiccate at -20°C
Synonyms EACA; Epsilon-Amino-n-caproic Acid; 6-Aminohexanoic acid
Solubility H2O : ≥ 50 mg/mL (381.18 mM)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
*"≥" means soluble, but saturation unknown.
Chemical Name 6-aminohexanoic acid
SMILES NCCCCCC(O)=O
Standard InChIKey SLXKOJJOQWFEFD-UHFFFAOYSA-N
Standard InChI InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of (6-)ε-​Aminocaproic acid

Description6-Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties. Target: Others 6-aminohexanoic acid is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis. Aminocaproic acid is also an intermediate in the polymerization of Nylon-6, where it is formed by ring-opening hydrolysis of caprolactam. Aminocaproic acid is used to treat excessive postoperative bleeding, especially after procedures in which a great amount of bleeding is expected, such as cardiac surgery. Aminocaproic acid can also be used to treat the overdose and/or toxic effects of the thrombolytic pharmacologic agents tissue plasminogen activator and streptokinase [1, 2].

References:
[1]. Gardner, F.H. and R.E. Helmer, 3rd, Aminocaproic acid. Use in control of hemorrhage in patients with amegakaryocytic thrombocytopenia. JAMA, 1980. 243(1): p. 35-7. [2]. Schwartz, B.S., et al., Epsilon-aminocaproic acid in the treatment of patients with acute promyelocytic leukemia and acquired alpha-2-plasmin inhibitor deficiency. Ann Intern Med, 1986. 105(6): p. 873-7.

(6-)ε-​Aminocaproic acid Dilution Calculator

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(6-)ε-​Aminocaproic acid Molarity Calculator

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Preparing Stock Solutions of (6-)ε-​Aminocaproic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 7.6237 mL 38.1185 mL 76.2369 mL 152.4739 mL 190.5924 mL
5 mM 1.5247 mL 7.6237 mL 15.2474 mL 30.4948 mL 38.1185 mL
10 mM 0.7624 mL 3.8118 mL 7.6237 mL 15.2474 mL 19.0592 mL
50 mM 0.1525 mL 0.7624 mL 1.5247 mL 3.0495 mL 3.8118 mL
100 mM 0.0762 mL 0.3812 mL 0.7624 mL 1.5247 mL 1.9059 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on (6-)ε-​Aminocaproic acid

6-Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.

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Description

6-Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.

Keywords:

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