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1,7-Dihydroxyacridone

CAS# 112649-95-3

1,7-Dihydroxyacridone

Catalog No. BCN7275----Order now to get a substantial discount!

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1,7-Dihydroxyacridone: 5mg $886 In Stock
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Quality Control of 1,7-Dihydroxyacridone

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Chemical structure

1,7-Dihydroxyacridone

3D structure

Chemical Properties of 1,7-Dihydroxyacridone

Cas No. 112649-95-3 SDF Download SDF
PubChem ID 13857937 Appearance Powder
Formula C13H9NO3 M.Wt 227.21
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1,7-dihydroxy-10H-acridin-9-one
SMILES C1=CC2=C(C(=C1)O)C(=O)C3=C(N2)C=CC(=C3)O
Standard InChIKey KXKWBGSBYIZPDQ-UHFFFAOYSA-N
Standard InChI InChI=1S/C13H9NO3/c15-7-4-5-9-8(6-7)13(17)12-10(14-9)2-1-3-11(12)16/h1-6,15-16H,(H,14,17)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 1,7-Dihydroxyacridone

The herbs of Boenninghausenia albiflora.

Biological Activity of 1,7-Dihydroxyacridone

Description1,7-Dihydroxyacridone is a natural product from Boenninghausenia albiflora.

Protocol of 1,7-Dihydroxyacridone

Structure Identification
Supplements to Edition of Rodds Chemistry of Carbon Compounds, 1975:245-258.

Sainsbury M. Chapter 32–The acridine alkaloids.[Reference: WebLink]

This chapter provides an overview of the acridine alkaloids. Gravacridone triol represents a new alkaloid from Ruta graveolens, where it co-occurs with its monoglucosyl derivative and the glucoside of a known alkaloid gravacridone diol.
METHODS AND RESULTS:
The 5-hydroxy derivative of the known alkaloid arborinine has been obtained for the first time from the leaves of Glycosmis bilocularis. Two other acridones differing only in the presence or absence of methoxyl groups are the alkaloids and isolated from the leaves of Bauerella simplicifolia. Boenninghausenia albiflora produces 1-hydroxyacridone and possibly also 1,7-Dihydroxyacridone.
CONCLUSIONS:
Two new acridones, 1-hydroxy-3,4-dimethoxy-10-methylacridone and l-hydroxy-3-geranyloxy-4-methoxy-10-methylacridone occur in extracts of the plant Sarcomelicope leiocarpa indigenous to New Caledonia together with eight other known structures. Another series of related alkaloids are produced by the plant Glycosmis citrifolia; these include the acridones glycocitrine-I, glycocitrine-II, its o-methyl ether, glyfoline, furofoline-II, and pyranofoline.

1,7-Dihydroxyacridone Dilution Calculator

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1,7-Dihydroxyacridone Molarity Calculator

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Preparing Stock Solutions of 1,7-Dihydroxyacridone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4012 mL 22.0061 mL 44.0121 mL 88.0243 mL 110.0304 mL
5 mM 0.8802 mL 4.4012 mL 8.8024 mL 17.6049 mL 22.0061 mL
10 mM 0.4401 mL 2.2006 mL 4.4012 mL 8.8024 mL 11.003 mL
50 mM 0.088 mL 0.4401 mL 0.8802 mL 1.7605 mL 2.2006 mL
100 mM 0.044 mL 0.2201 mL 0.4401 mL 0.8802 mL 1.1003 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 1,7-Dihydroxyacridone

Sainsbury M. Chapter 32–The acridine alkaloids.

Supplements to Edition of Rodds Chemistry of Carbon Compounds, 1975:245-258.

This chapter provides an overview of the acridine alkaloids. Gravacridone triol represents a new alkaloid from Ruta graveolens, where it co-occurs with its monoglucosyl derivative and the glucoside of a known alkaloid gravacridone diol. The 5-hydroxy derivative of the known alkaloid arborinine has been obtained for the first time from the leaves of Glycosmis bilocularis. Two other acridones differing only in the presence or absence of methoxyl groups are the alkaloids and isolated from the leaves of Bauerella simplicifolia. Boenninghausenia albiflora produces 1-hydroxyacridone and possibly also 1,7-Dihydroxyacridone. Two new acridones, 1-hydroxy-3,4-dimethoxy-10-methylacridone and l-hydroxy-3-geranyloxy-4-methoxy-10-methylacridone occur in extracts of the plant Sarcomelicope leiocarpa indigenous to New Caledonia together with eight other known structures. Another series of related alkaloids are produced by the plant Glycosmis citrifolia; these include the acridones glycocitrine-I, glycocitrine-II, its o-methyl ether, glyfoline, furofoline-II, and pyranofoline.

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