Home >> Research Area >>Natural Products>>Chalcones>> 2',4'-Dihydroxychalcone

2',4'-Dihydroxychalcone

CAS# 1776-30-3

2',4'-Dihydroxychalcone

Catalog No. BCN5647----Order now to get a substantial discount!

Product Name & Size Price Stock
2',4'-Dihydroxychalcone: 5mg Please Inquire In Stock
2',4'-Dihydroxychalcone: 10mg Please Inquire In Stock
2',4'-Dihydroxychalcone: 20mg Please Inquire Please Inquire
2',4'-Dihydroxychalcone: 50mg Please Inquire Please Inquire
2',4'-Dihydroxychalcone: 100mg Please Inquire Please Inquire
2',4'-Dihydroxychalcone: 200mg Please Inquire Please Inquire
2',4'-Dihydroxychalcone: 500mg Please Inquire Please Inquire
2',4'-Dihydroxychalcone: 1000mg Please Inquire Please Inquire

Quality Control of 2',4'-Dihydroxychalcone

Number of papers citing our products

Chemical structure

2',4'-Dihydroxychalcone

3D structure

Chemical Properties of 2',4'-Dihydroxychalcone

Cas No. 1776-30-3 SDF Download SDF
PubChem ID 5376979 Appearance Yellow powder
Formula C15H12O3 M.Wt 240.26
Type of Compound Chalcones Storage Desiccate at -20°C
Synonyms (E)-2',4'-Dihydroxychalcone
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (E)-1-(2,4-dihydroxyphenyl)-3-phenylprop-2-en-1-one
SMILES C1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2)O)O
Standard InChIKey JUMSUVHHUVPSOY-RMKNXTFCSA-N
Standard InChI InChI=1S/C15H12O3/c16-12-7-8-13(15(18)10-12)14(17)9-6-11-4-2-1-3-5-11/h1-10,16,18H/b9-6+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2',4'-Dihydroxychalcone

The roots of Glycyrrhiza glabra L.

2',4'-Dihydroxychalcone Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

2',4'-Dihydroxychalcone Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 2',4'-Dihydroxychalcone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.1622 mL 20.8108 mL 41.6216 mL 83.2432 mL 104.0539 mL
5 mM 0.8324 mL 4.1622 mL 8.3243 mL 16.6486 mL 20.8108 mL
10 mM 0.4162 mL 2.0811 mL 4.1622 mL 8.3243 mL 10.4054 mL
50 mM 0.0832 mL 0.4162 mL 0.8324 mL 1.6649 mL 2.0811 mL
100 mM 0.0416 mL 0.2081 mL 0.4162 mL 0.8324 mL 1.0405 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 2',4'-Dihydroxychalcone

In Vitro Antifungal Activity and Mode of Action of 2',4'-Dihydroxychalcone against Aspergillus fumigatus.[Pubmed:26190922]

Mycobiology. 2015 Jun;43(2):150-6.

2',4'-Dihydroxychalcone (2',4'-DHC) was identified from a heat shock protein 90 (Hsp90)-targeting library as a compound with Hsp90 inhibitory and antifungal effects. In the presence of 2',4'-DHC (8 microg/mL), radial growth of Aspergillus fumigatus was inhibited 20% compared to the control, and green pigmentation was completely blocked. The expression of the conidiation-associated genes abaA, brlA, and wetA was significantly decreased (approximately 3- to 5-fold) by treatment with 2',4'-DHC. The expression of calcineurin signaling components, cnaA and crzA, was also significantly reduced. The inhibitory effects of 2',4'-DHC on metabolic activity and mycelial growth were significantly enhanced by combination treatment with itraconazole and caspofungin. Docking studies indicated that 2',4'-DHC bind to the ATPase domain of Hsp90. These results suggest that 2',4'-DHC act as an Hsp90-calcinurin pathway inhibitor.

Keywords:

2',4'-Dihydroxychalcone,1776-30-3,(E)-2',4'-Dihydroxychalcone,Natural Products, buy 2',4'-Dihydroxychalcone , 2',4'-Dihydroxychalcone supplier , purchase 2',4'-Dihydroxychalcone , 2',4'-Dihydroxychalcone cost , 2',4'-Dihydroxychalcone manufacturer , order 2',4'-Dihydroxychalcone , high purity 2',4'-Dihydroxychalcone

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: