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5-Amino-2-naphthalenesulfonic acid

CAS# 119-79-9

5-Amino-2-naphthalenesulfonic acid

Catalog No. BCC8732----Order now to get a substantial discount!

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5-Amino-2-naphthalenesulfonic acid: 5mg $17 In Stock
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Chemical structure

5-Amino-2-naphthalenesulfonic acid

3D structure

Chemical Properties of 5-Amino-2-naphthalenesulfonic acid

Cas No. 119-79-9 SDF Download SDF
PubChem ID 8408 Appearance Powder
Formula C10H9NO3S M.Wt 223
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5-aminonaphthalene-2-sulfonic acid
SMILES C1=CC2=C(C=CC(=C2)S(=O)(=O)O)C(=C1)N
Standard InChIKey UWPJYQYRSWYIGZ-UHFFFAOYSA-N
Standard InChI InChI=1S/C10H9NO3S/c11-10-3-1-2-7-6-8(15(12,13)14)4-5-9(7)10/h1-6H,11H2,(H,12,13,14)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

5-Amino-2-naphthalenesulfonic acid Dilution Calculator

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5-Amino-2-naphthalenesulfonic acid Molarity Calculator

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Preparing Stock Solutions of 5-Amino-2-naphthalenesulfonic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4843 mL 22.4215 mL 44.843 mL 89.6861 mL 112.1076 mL
5 mM 0.8969 mL 4.4843 mL 8.9686 mL 17.9372 mL 22.4215 mL
10 mM 0.4484 mL 2.2422 mL 4.4843 mL 8.9686 mL 11.2108 mL
50 mM 0.0897 mL 0.4484 mL 0.8969 mL 1.7937 mL 2.2422 mL
100 mM 0.0448 mL 0.2242 mL 0.4484 mL 0.8969 mL 1.1211 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 5-Amino-2-naphthalenesulfonic acid

Anti-angiogenic activity of heparin-like polysulfonated polymeric drugs in 3D human cell culture.[Pubmed:20674006]

Biomaterials. 2010 Nov;31(31):7863-72.

The activity of new anti-angiogenic polymeric drugs was tested in a 3D endothelial cell culture system applied as a model of angiogenesis. The assay was performed in a highly reproducible fibrin matrix that supported endothelial cell attachment, proliferation, migration, and formation of capillary-like structures. Active growth factors (FGF and/or VEGF) were added to the medium to induce the formation of blood vessel-like structures, and the effect of the active polymers was then tested by a semi-quantitative immunostaining protocol and visualized by laser-scanning confocal microscopy. The synthetic heparin-like macromolecules that were tested for their anti-angiogenic efficacy were previously characterized in terms of their anti-proliferative activity in 2D tissue culture. Two different anti-angiogenic monomers, a methacrylic derivative of 5-Amino-2-naphthalenesulfonic acid (MANSA) and 2-acrylamido-2-methylpropane sulfonic acid (AMPS), were copolymerized with a hydrophilic monomer (vinyl pyrrolidone, VP) or a hydrophobic monomer (butyl acrylate, BA), giving rise to different copolymeric systems with controlled microstructure and supramolecular organization. Both copolymeric systems have demonstrated a composition-dependent anti-mitogenic effect in "2D in vitro" cell culture experiments using aFGF as pro-angiogenic growth factor and BALB/c 3T3 fibroblast as cell model, as was shown in a previous publication. These 3D experiments provide evidence for the strong and specific modulation of angiogenesis by these systems. The 3D experiments constitute an improvement over 2D in vitro experiments and in vivo experiments with angiogenic drugs and may help to reduce the number of animal experiments.

An analytical system for the characterization of highly heterogeneous mixtures of N-linked oligosaccharides.[Pubmed:19281790]

Anal Biochem. 2009 Jun 1;389(1):40-51.

A novel system for characterizing complex N-linked oligosaccharide mixtures that uses a combination of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), capillary electrophoresis (CE), and high-performance liquid chromatography (HPLC) has been developed. In this study, oligosaccharides released from recombinant TNK-tPA (tissue plasminogen activator) were derivatized with 5-Amino-2-naphthalenesulfonic acid (ANSA). The negative charge imparted by the ANSA label facilitated the analysis of the oligosaccharides by MALDI-TOF MS by allowing the observation of both neutral and sialylated oligosaccharides in a single negative ion mode spectrum. Labeling with ANSA was also determined to be advantageous in the characterization of oligosaccharides by both HPLC and CE. The ANSA label was demonstrated to provide superior resolution over the commonly used label 8-aminopyrene-1,3,6-trisulfonic acid (APTS) in both the CE and HPLC analysis of oligosaccharides. To date, no other labels that enable the analysis of complex oligosaccharide mixtures in a single mass spectral mode, while also enabling high-resolution chromatographic and electrophoretic separation of the oligosaccharides, have been reported. By integrating the structural information obtained by MALDI-TOF MS analysis with the ability of CE and HPLC to discriminate between structural isomers, the complete characterization of complex oligosaccharide mixtures is possible.

Poly(3,4-ethylenedioxythiophene-co-(5-amino-2-naphthalenesulfonic acid)) (PEDOT-PANS) film modified glassy carbon electrode for selective detection of dopamine in the presence of ascorbic acid and uric acid.[Pubmed:17616245]

Anal Chim Acta. 2007 Jul 16;596(1):92-8.

Poly(3,4-ethylenedioxythiophene-co-(5-Amino-2-naphthalenesulfonic acid)) (PEDOT-PANS) film modified glassy carbon electrode was prepared by electrochemical polymerization technique. The properties of modified electrode was studied. It was found that the electrochemical properties of modified electrode was very much dependent on the experimental conditions, such as monomer oxidation potential and pH. The modified electrode surface was characterized by scanning electron microscopy (SEM). The PEDOT-PANS film modified electrode shows electrocatalytic activity toward oxidation of dopamine (DA) in acetate buffer solution (pH 5.0) and results in a marked enhancement of the current response. The linear sweep voltammetric (LSV) peak heights are linear with DA concentration from 2x10(-6) to 1x10(-5) M. The detection limit is 5x10(-7) M. More over, the interferences of ascorbic acid (AA) and uric acid (UA) were effectively diminished. This work provides a simple and easy approach for selective determination of dopamine in the presence of ascorbic acid and uric acid.

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