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5-Hydroxy-2-pyrrolidinone

CAS# 62312-55-4

5-Hydroxy-2-pyrrolidinone

Catalog No. BCN4155----Order now to get a substantial discount!

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5-Hydroxy-2-pyrrolidinone: 5mg Please Inquire In Stock
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Quality Control of 5-Hydroxy-2-pyrrolidinone

Number of papers citing our products

Chemical structure

5-Hydroxy-2-pyrrolidinone

3D structure

Chemical Properties of 5-Hydroxy-2-pyrrolidinone

Cas No. 62312-55-4 SDF Download SDF
PubChem ID 194148 Appearance Powder
Formula C4H7NO2 M.Wt 101.1
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5-hydroxypyrrolidin-2-one
SMILES C1CC(=O)NC1O
Standard InChIKey WBGWUCXEMSSZJL-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 5-Hydroxy-2-pyrrolidinone

The herbs of Buddleja asiatica

Biological Activity of 5-Hydroxy-2-pyrrolidinone

DescriptionStandard reference

Protocol of 5-Hydroxy-2-pyrrolidinone

Structure Identification
Life Sci. 1984 Nov 26;35(22):2205-12.

2-Pyrrolidinone and succinimide endogenously present in several mammalian species.[Pubmed: 6503611]


METHODS AND RESULTS:
2-Pyrrolidinone and succinimide were identified in blood plasma of man, rat, and mouse. Dog plasma contained only traces of 2-pyrrolidinone not exceeding significantly the detection limit of our GCMS-method. Succinimide but not 2-pyrrolidinone could also be found in the brains of rat and mouse.
CONCLUSIONS:
Evidence is presented for a metabolic pathway leading from 2-pyrrolidinone to succinimide, with 5-Hydroxy-2-pyrrolidinone as an intermediate.

5-Hydroxy-2-pyrrolidinone Dilution Calculator

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5-Hydroxy-2-pyrrolidinone Molarity Calculator

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Preparing Stock Solutions of 5-Hydroxy-2-pyrrolidinone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 9.8912 mL 49.456 mL 98.912 mL 197.8239 mL 247.2799 mL
5 mM 1.9782 mL 9.8912 mL 19.7824 mL 39.5648 mL 49.456 mL
10 mM 0.9891 mL 4.9456 mL 9.8912 mL 19.7824 mL 24.728 mL
50 mM 0.1978 mL 0.9891 mL 1.9782 mL 3.9565 mL 4.9456 mL
100 mM 0.0989 mL 0.4946 mL 0.9891 mL 1.9782 mL 2.4728 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 5-Hydroxy-2-pyrrolidinone

2-Pyrrolidinone and succinimide endogenously present in several mammalian species.[Pubmed:6503611]

Life Sci. 1984 Nov 26;35(22):2205-12.

2-Pyrrolidinone and succinimide were identified in blood plasma of man, rat, and mouse. Dog plasma contained only traces of 2-pyrrolidinone not exceeding significantly the detection limit of our GCMS-method. Succinimide but not 2-pyrrolidinone could also be found in the brains of rat and mouse. Evidence is presented for a metabolic pathway leading from 2-pyrrolidinone to succinimide, with 5-Hydroxy-2-pyrrolidinone as an intermediate.

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