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5-Methoxy-7-hydroxycoumarin

CAS# 3067-10-5

5-Methoxy-7-hydroxycoumarin

Catalog No. BCN3538----Order now to get a substantial discount!

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5-Methoxy-7-hydroxycoumarin: 5mg Please Inquire In Stock
5-Methoxy-7-hydroxycoumarin: 10mg Please Inquire In Stock
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Quality Control of 5-Methoxy-7-hydroxycoumarin

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Chemical structure

5-Methoxy-7-hydroxycoumarin

3D structure

Chemical Properties of 5-Methoxy-7-hydroxycoumarin

Cas No. 3067-10-5 SDF Download SDF
PubChem ID 5487854 Appearance Powder
Formula C10H8O4 M.Wt 192.2
Type of Compound Coumarins Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 7-hydroxy-5-methoxychromen-2-one
SMILES COC1=C2C=CC(=O)OC2=CC(=C1)O
Standard InChIKey IFIRYJJHHOCCHT-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 5-Methoxy-7-hydroxycoumarin

The peel of Citrus medica L.

Biological Activity of 5-Methoxy-7-hydroxycoumarin

Description1. 7-Hydroxy-5-methoxycoumarin, has been found to be a moderate inhibitor for aldehyde oxidase, a molybdo-flavoenzymes, it inhibits the release of superoxide anion more efficiently than hydrogen peroxide or substrate oxidation.

5-Methoxy-7-hydroxycoumarin Dilution Calculator

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5-Methoxy-7-hydroxycoumarin Molarity Calculator

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Preparing Stock Solutions of 5-Methoxy-7-hydroxycoumarin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2029 mL 26.0146 mL 52.0291 mL 104.0583 mL 130.0728 mL
5 mM 1.0406 mL 5.2029 mL 10.4058 mL 20.8117 mL 26.0146 mL
10 mM 0.5203 mL 2.6015 mL 5.2029 mL 10.4058 mL 13.0073 mL
50 mM 0.1041 mL 0.5203 mL 1.0406 mL 2.0812 mL 2.6015 mL
100 mM 0.052 mL 0.2601 mL 0.5203 mL 1.0406 mL 1.3007 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 5-Methoxy-7-hydroxycoumarin

Comparative Effects of Scopoletin and Menadione on Aldehyde Oxidase Activity of Guinea Pig Liver

J. Biol. Sci., 2005, 5(4):525-31.

Scopoletin, 7-hydroxy-5-methoxycoumarin, has been found to be a moderate inhibitor for aldehyde oxidase, a molybdo-flavoenzymes. It inhibits the release of superoxide anion more efficiently than hydrogen peroxide or substrate oxidation. Statistically, the inhibition of three-specific aldehyde oxidase substrates was significant (p<0.005) in the presence of 100 ?M Scopoletin. A progressive and non-competitive inhibition has been observed with inhibitor constant (Ki) value of 57.2?3.3 ?M using indole-3-aldehyde and oxygen as a substrate and electron acceptor, respectively. A specific site for interaction between Scopoletin and aldehyde oxidase has been proposed and its effect on the reactive oxygen species production has been discussed. The effect of Scopoletin on aldehyde oxidase activity has been compared with that of traditional and specific inhibitors, such as menadione.

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