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6-Hydroxykaempferol

CAS# 4324-55-4

6-Hydroxykaempferol

Catalog No. BCN3334----Order now to get a substantial discount!

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Quality Control of 6-Hydroxykaempferol

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Chemical structure

6-Hydroxykaempferol

3D structure

Chemical Properties of 6-Hydroxykaempferol

Cas No. 4324-55-4 SDF Download SDF
PubChem ID 5281638 Appearance Yellow powder
Formula C15H10O7 M.Wt 302.2
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3,5,6,7-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one
SMILES C1=CC(=CC=C1C2=C(C(=O)C3=C(C(=C(C=C3O2)O)O)O)O)O
Standard InChIKey LFPHMXIOQBBTSS-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 6-Hydroxykaempferol

The herbs of Inula japonica Thunb.

Biological Activity of 6-Hydroxykaempferol

Description1. 6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
TargetsTyrosinase

6-Hydroxykaempferol Dilution Calculator

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6-Hydroxykaempferol Molarity Calculator

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Preparing Stock Solutions of 6-Hydroxykaempferol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3091 mL 16.5453 mL 33.0907 mL 66.1813 mL 82.7267 mL
5 mM 0.6618 mL 3.3091 mL 6.6181 mL 13.2363 mL 16.5453 mL
10 mM 0.3309 mL 1.6545 mL 3.3091 mL 6.6181 mL 8.2727 mL
50 mM 0.0662 mL 0.3309 mL 0.6618 mL 1.3236 mL 1.6545 mL
100 mM 0.0331 mL 0.1655 mL 0.3309 mL 0.6618 mL 0.8273 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 6-Hydroxykaempferol

Inhibitory effects of 5,6,7-trihydroxyflavones on tyrosinase.[Pubmed:17693955]

Molecules. 2007 Jan 29;12(1):86-97.

Baicalein (1), 6-hydroxyapigenin (6), 6-hydroxygalangin (13) and 6-hydroxy-kaempferol (14), which are naturally occurring flavonoids from a set of 14 hydroxy-flavones tested, exhibited high inhibitory effects on tyrosinase with respect to L-DOPA, while each of the 5,6,7-trihydroxyflavones 1, 6, 13 or 14 acted as a cofactor to monophenolase. Moreover, 6-Hydroxykaempferol (14) showed the highest activity and was a competitive inhibitor of tyrosinase compared to L-DOPA. 5,6,7-Trihydroxyflavones 1, 6, 13 or 14 showed also high antioxidant activities. Hence, we conclude that the 5,6,7-trihydroxy-flavones are useful as good depigmentation agents with inhibitory effects in addition to their antioxidant properties.

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