AVX 13616

CAS# 900814-48-4

AVX 13616

Catalog No. BCC5407----Order now to get a substantial discount!

Product Name & Size Price Stock
AVX 13616: 5mg $380 In Stock
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Chemical structure

AVX 13616

3D structure

Chemical Properties of AVX 13616

Cas No. 900814-48-4 SDF Download SDF
PubChem ID 75165259 Appearance Powder
Formula C50H73Cl2N7O7 M.Wt 955.06
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3-methylbutyl 2-[[2-[[6-amino-2-[[2-[1-[2-(3-methylbutoxy)naphthalen-1-yl]naphthalen-2-yl]oxyacetyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoate;dihydrochloride
SMILES CC(C)CCOC1=C(C2=CC=CC=C2C=C1)C3=C(C=CC4=CC=CC=C43)OCC(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC(C)C)C(=O)OCCC(C)C.Cl.Cl
Standard InChIKey SINJZCNZEBJUKD-UHFFFAOYSA-N
Standard InChI InChI=1S/C50H71N7O7.2ClH/c1-32(2)24-28-62-42-22-20-35-14-7-9-16-37(35)45(42)46-38-17-10-8-15-36(38)21-23-43(46)64-31-44(58)55-39(18-11-12-26-51)47(59)56-40(19-13-27-54-50(52)53)48(60)57-41(30-34(5)6)49(61)63-29-25-33(3)4;;/h7-10,14-17,20-23,32-34,39-41H,11-13,18-19,24-31,51H2,1-6H3,(H,55,58)(H,56,59)(H,57,60)(H4,52,53,54);2*1H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

AVX 13616 Dilution Calculator

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AVX 13616 Molarity Calculator

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Preparing Stock Solutions of AVX 13616

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0471 mL 5.2353 mL 10.4705 mL 20.9411 mL 26.1764 mL
5 mM 0.2094 mL 1.0471 mL 2.0941 mL 4.1882 mL 5.2353 mL
10 mM 0.1047 mL 0.5235 mL 1.0471 mL 2.0941 mL 2.6176 mL
50 mM 0.0209 mL 0.1047 mL 0.2094 mL 0.4188 mL 0.5235 mL
100 mM 0.0105 mL 0.0524 mL 0.1047 mL 0.2094 mL 0.2618 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

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Yale University

Worcester Polytechnic Institute

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Universidade da Beira Interior

The Institute of Cancer Research

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University of Auckland
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The University of Michigan
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DRURY University
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Jilin University
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Sun Yat-sen University
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Universite de Paris
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Auckland University
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The University of Tokyo
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Korea University
Korea University

Background on AVX 13616

AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens. IC50 value: 2-4 ug/ml (MICs) Target: antibacterial agent AVX13616 was as active as mupirocin in a nasal decolonization model but required only a single application. The compounds are being developed for topical indications and/or wound infection/catheter-related infections. AVX13616 and other compounds showed broad spectrum antibacterial activity against a range of isolates with MICs of 2-4 micrograms per millilitre against S. aureus, coagulase negative staphylococci, enterococci, MRSA, VISA and VRSA. A single application of 5% (w/w) AVX13616 (approximately equimolar to 2% mupirocin) was as effective as 2% mupirocin administered twice a day for five days in nasal decolonisation of MRSA in mice.

References:
[1]. Avexa Presents Data from Apricitabine and Antibacterial Programs at two International Conferences

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Description

AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens.

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