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Apiopaeonoside

CAS# 100291-86-9

Apiopaeonoside

Catalog No. BCN2801----Order now to get a substantial discount!

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Apiopaeonoside: 5mg $40 In Stock
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Quality Control of Apiopaeonoside

Number of papers citing our products

Chemical structure

Apiopaeonoside

3D structure

Chemical Properties of Apiopaeonoside

Cas No. 100291-86-9 SDF Download SDF
PubChem ID 127509 Appearance Powder
Formula C20H28O12 M.Wt 460.43
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-[2-[6-[[3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]oxy-4-methoxyphenyl]ethanone
SMILES CC(=O)C1=C(C=C(C=C1)OC)OC2C(C(C(C(O2)COC3C(C(CO3)(CO)O)O)O)O)O
Standard InChIKey IRLNKOAURQPXIQ-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Apiopaeonoside

The root of Paeonia lactiflora Pall.

Biological Activity of Apiopaeonoside

DescriptionApiopaeonoside is a natural product from Paeonia suffruticosa.
In vivo

Protective constituents against sepsis in mice from the root cortex of Paeonia suffruticosa.[Pubmed: 15595414 ]

Arch Pharm Res. 2004 Nov;27(11):1123-6.


METHODS AND RESULTS:
The bioassay-guided fractionation of protective agents against sepsis-induced lethality from the root cortex of Paeonia suffruticosa ANDREWS (Ranunculaceae) led to the isolation of eight known compounds: paeonol (1), 2,5-dihydroxy-4-methoxyacetophenone (2), acetovanillone (3), paeonoside (4), paeoniflorin (5), oxypaeoniflorin (6), Apiopaeonoside (7), and methyl 3-hydroxy-4-methoxybenzoate (8).
CONCLUSIONS:
Among them, 3 showed the highest survival rate (100% with a dose of 30 mg/kg versus 17% for the control experiment) and reduced alanine aminotransferase level to be a half of the control value on the sepsis model induced by lipopolysaccharide/D-galactosamine.

Apiopaeonoside Dilution Calculator

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Apiopaeonoside Molarity Calculator

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Preparing Stock Solutions of Apiopaeonoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1719 mL 10.8594 mL 21.7188 mL 43.4377 mL 54.2971 mL
5 mM 0.4344 mL 2.1719 mL 4.3438 mL 8.6875 mL 10.8594 mL
10 mM 0.2172 mL 1.0859 mL 2.1719 mL 4.3438 mL 5.4297 mL
50 mM 0.0434 mL 0.2172 mL 0.4344 mL 0.8688 mL 1.0859 mL
100 mM 0.0217 mL 0.1086 mL 0.2172 mL 0.4344 mL 0.543 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Apiopaeonoside

Protective constituents against sepsis in mice from the root cortex of Paeonia suffruticosa.[Pubmed:15595414]

Arch Pharm Res. 2004 Nov;27(11):1123-6.

The bioassay-guided fractionation of protective agents against sepsis-induced lethality from the root cortex of Paeonia suffruticosa ANDREWS (Ranunculaceae) led to the isolation of eight known compounds: paeonol (1), 2,5-dihydroxy-4-methoxyacetophenone (2), acetovanillone (3), paeonoside (4), paeoniflorin (5), oxypaeoniflorin (6), Apiopaeonoside (7), and methyl 3-hydroxy-4-methoxybenzoate (8). Among them, 3 showed the highest survival rate (100% with a dose of 30 mg/kg versus 17% for the control experiment) and reduced alanine aminotransferase level to be a half of the control value on the sepsis model induced by lipopolysaccharide/D-galactosamine.

Description

Apiopaeonoside is a natural product isolated from the root of Paeonia suffruticosa.

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