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Cimicifugoside H2

CAS# 161097-77-4

Cimicifugoside H2

Catalog No. BCN7949----Order now to get a substantial discount!

Product Name & Size Price Stock
Cimicifugoside H2: 5mg Please Inquire In Stock
Cimicifugoside H2: 10mg Please Inquire In Stock
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Quality Control of Cimicifugoside H2

Number of papers citing our products

Chemical structure

Cimicifugoside H2

3D structure

Chemical Properties of Cimicifugoside H2

Cas No. 161097-77-4 SDF Download SDF
PubChem ID 10100589 Appearance Powder
Formula C35H54O10 M.Wt 634.8
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(CC(=O)C(C(C)(C)O)O)C1C(=O)CC2(C1(CC(C34C2=CCC5C3(C4)CCC(C5(C)C)OC6C(C(C(CO6)O)O)O)O)C)C
Standard InChIKey SUNYLGIAMKNXMN-GLWILYKISA-N
Standard InChI InChI=1S/C35H54O10/c1-17(12-18(36)28(42)31(4,5)43)25-19(37)13-32(6)22-9-8-21-30(2,3)24(45-29-27(41)26(40)20(38)15-44-29)10-11-34(21)16-35(22,34)23(39)14-33(25,32)7/h9,17,20-21,23-29,38-43H,8,10-16H2,1-7H3/t17-,20-,21+,23+,24+,25+,26+,27-,28+,29+,32+,33-,34-,35+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cimicifugoside H2

The herbs of Cimicifuga foetida

Biological Activity of Cimicifugoside H2

DescriptionCimicifugoside H2 is a natural product from Cimicifuga foetida.

Protocol of Cimicifugoside H2

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1930-4.

Cycloartane triterpenoid of Cimicifuga foetida.[Pubmed: 19894537]

To study cycloartane triterpenoid of Cimicifuga foetida and their osteoclast inhibition activity.
METHODS AND RESULTS:
The compounds were isolated and purified by normal and reversed phase column chromatographic methods. Structures were identified by spectroscopic analyses. Their osteoclast inhibition activity was then studied.Thirteen cycloartane triterpenoids were isolated from the rhizomes of C. foetida and were characterized as 25-O-acetyl-cimigenol (1), cimigenol (2), cimicidanol (3), 26-deoxyactein (4), asiaticoside A (5), 23-epi-26-deoxyactein (6), actein (7), 12beta-hydroxycimigenol (8), cimiside E (9), (23R, 24S) 25-O-acetyl-cimigenol-3-O-beta-D-xylopyranoside (10), (23R, 24S) cimigenol-3-O-beta-D-xylopyranoside (11), cimicifugoside H1 (12) and Cimicifugoside H2 (13).
CONCLUSIONS:
Compound 5 was isolated from this genus for the first time, compound 7 was isolated firstly from the plant and compound 2, 7, 10 and 11 exhibit osteoclast inhibition activity.

Cimicifugoside H2 Dilution Calculator

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Cimicifugoside H2 Molarity Calculator

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Preparing Stock Solutions of Cimicifugoside H2

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5753 mL 7.8765 mL 15.753 mL 31.506 mL 39.3825 mL
5 mM 0.3151 mL 1.5753 mL 3.1506 mL 6.3012 mL 7.8765 mL
10 mM 0.1575 mL 0.7876 mL 1.5753 mL 3.1506 mL 3.9382 mL
50 mM 0.0315 mL 0.1575 mL 0.3151 mL 0.6301 mL 0.7876 mL
100 mM 0.0158 mL 0.0788 mL 0.1575 mL 0.3151 mL 0.3938 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cimicifugoside H2

[Cycloartane triterpenoid of Cimicifuga foetida].[Pubmed:19894537]

Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1930-4.

OBJECTIVE: To study cycloartane triterpenoid of Cimicifuga foetida and their osteoclast inhibition activity. METHOD: The compounds were isolated and purified by normal and reversed phase column chromatographic methods. Structures were identified by spectroscopic analyses. Their osteoclast inhibition activity was then studied. RESULT: Thirteen cycloartane triterpenoids were isolated from the rhizomes of C. foetida and were characterized as 25-O-acetyl-cimigenol (1), cimigenol (2), cimicidanol (3), 26-deoxyactein (4), asiaticoside A (5), 23-epi-26-deoxyactein (6), actein (7), 12beta-hydroxycimigenol (8), cimiside E (9), (23R, 24S) 25-O-acetyl-cimigenol-3-O-beta-D-xylopyranoside (10), (23R, 24S) cimigenol-3-O-beta-D-xylopyranoside (11), cimicifugoside H-1 (12) and cimicifugoside H-2 (13). CONCLUSION: Compound 5 was isolated from this genus for the first time, compound 7 was isolated firstly from the plant and compound 2, 7, 10 and 11 exhibit osteoclast inhibition activity.

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