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Clemaphenol A

CAS# 362606-60-8

Clemaphenol A

Catalog No. BCN7834----Order now to get a substantial discount!

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Quality Control of Clemaphenol A

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Chemical structure

Clemaphenol A

3D structure

Chemical Properties of Clemaphenol A

Cas No. 362606-60-8 SDF Download SDF
PubChem ID 46173999 Appearance Powder
Formula C20H22O6 M.Wt 358.39
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5-[(3S,3aR,6S,6aR)-6-(3-hydroxy-4-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol
SMILES COC1=C(C=C(C=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)OC)O)O
Standard InChIKey VRHZMFGDDGFRLP-AFHBHXEDSA-N
Standard InChI InChI=1S/C20H22O6/c1-23-17-5-3-11(7-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-18(24-2)16(22)8-12/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Clemaphenol A

The whole plants of Cynanchum auriculatum.

Biological Activity of Clemaphenol A

DescriptionClemaphenol A is a natural product from Cynanchum auriculatum.

Protocol of Clemaphenol A

Structure Identification
Zhong Yao Cai. 2015 Nov;38(11):2318-20.

Chemical Constituents of Cynanchum auriculatum.[Pubmed: 27356383]

To study the chemical constituents of Cynanchum auriculatum.
METHODS AND RESULTS:
Nine compounds were isolated by silica gel, RP-18 column chromatography and Sephadex LH20. Nine compounds were isolated from the ethanol extract of Cynanchum auriculatum. Their structures were determined as sarcosin-3-O-β-cymaropyranoside (1), cynotophylloside B (2), Clemaphenol A (3), deacetylmetaplexigenin (4), methyl-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl- (1 --> 4) -6-deoxy-3-O-methyl-α-L-ribo-hexopyranoside (5), trans-p-hydroxy cinnamic methyl ester (6), cyclo(D-Pro-D-Leu) (7), 3α-hydroxy-5α ,6α-epoxy-7-megastigmen9-one (8) and ferulic acid methyl ester (9) on the basis of spectral analysis.
CONCLUSIONS:
Compounds 3, 5 and 6 - 9 are isolated from Cynanchum auriculatum for the first time.

Clemaphenol A Dilution Calculator

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Clemaphenol A Molarity Calculator

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Preparing Stock Solutions of Clemaphenol A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7903 mL 13.9513 mL 27.9026 mL 55.8051 mL 69.7564 mL
5 mM 0.5581 mL 2.7903 mL 5.5805 mL 11.161 mL 13.9513 mL
10 mM 0.279 mL 1.3951 mL 2.7903 mL 5.5805 mL 6.9756 mL
50 mM 0.0558 mL 0.279 mL 0.5581 mL 1.1161 mL 1.3951 mL
100 mM 0.0279 mL 0.1395 mL 0.279 mL 0.5581 mL 0.6976 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Clemaphenol A

[Chemical Constituents of Cynanchum auriculatum].[Pubmed:27356383]

Zhong Yao Cai. 2015 Nov;38(11):2318-20.

OBJECTIVE: To study the chemical constituents of Cynanchum auriculatum. METHODS: Nine compounds were isolated by silica gel, RP-18 column chromatography and Sephadex LH20. RESULTS: Nine compounds were isolated from the ethanol extract of Cynanchum auriculatum. Their structures were determined as sarcosin-3-O-beta-cymaropyranoside (1), cynotophylloside B (2), Clemaphenol A (3), deacetylmetaplexigenin (4), methyl-2,6-dideoxy-3-O-methyl-beta-D-arabino-hexopyranosyl- (1 --> 4) -6-deoxy-3-O-methyl-alpha-L-ribo-hexopyranoside (5), trans-p-hydroxy cinnamic methyl ester (6), cyclo(D-Pro-D-Leu) (7), 3alpha-hydroxy-5alpha ,6alpha-epoxy-7-megastigmen9-one (8) and ferulic acid methyl ester (9) on the basis of spectral analysis. CONCLUSION: Compounds 3, 5 and 6 - 9 are isolated from Cynanchum auriculatum for the first time.

Description

Clemaphenol A is a chemical constituent of the flower of Fritillaria pallidiflora.

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