Coniferyl alcohol

CAS# 32811-40-8

Coniferyl alcohol

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Coniferyl alcohol: 5mg $615 In Stock
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Quality Control of Coniferyl alcohol

Number of papers citing our products

Chemical structure

Coniferyl alcohol

3D structure

Chemical Properties of Coniferyl alcohol

Cas No. 32811-40-8 SDF Download SDF
PubChem ID 1549095 Appearance Oil
Formula C10H12O3 M.Wt 180.20
Type of Compound Phenylpropanoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[(E)-3-hydroxyprop-1-enyl]-2-methoxyphenol
SMILES COC1=C(C=CC(=C1)C=CCO)O
Standard InChIKey JMFRWRFFLBVWSI-NSCUHMNNSA-N
Standard InChI InChI=1S/C10H12O3/c1-13-10-7-8(3-2-6-11)4-5-9(10)12/h2-5,7,11-12H,6H2,1H3/b3-2+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Coniferyl alcohol

The herbs of Acanthopanax gracilistylus

Biological Activity of Coniferyl alcohol

DescriptionConiferyl alcohol restores the growth of KI-treated BY-2 cells and N. benthamiana seedlings, at high concentrations is toxic to plant cells.
In vitro

Coniferyl alcohol hinders the growth of tobacco BY-2 cells and Nicotiana benthamiana seedlings.[Pubmed: 26108783]

Planta. 2015 Jun 25.

Externally added Coniferyl alcohol at high concentrations reduces the growth of Nicotiana cells and seedlings. Coniferyl alcohol is metabolized by BY-2 cells to several compounds. Coniferyl alcohol (CA) is a common monolignol and a building block of lignin. The toxicity of monolignol alcohols has been stated in the literature, but there are only few studies suggesting that this is true.
METHODS AND RESULTS:
We investigated the physiological effects of Coniferyl alcohol on living plant cells in more detail. Tobacco (Nicotiana tabacum) Bright yellow-2 cells (BY-2) and Nicotiana benthamiana seedlings both showed concentration-dependent growth retardation in response to 0.5-5 mM Coniferyl alcohol treatment. In some cases, Coniferyl alcohol addition caused cell death in BY-2 cultures, but this response was dependent on the growth stage of the cells. Based on LC-MS/MS analysis, BY-2 cells did not accumulate the externally supplemented Coniferyl alcohol, but metabolized it to ferulic acid, ferulic acid glycoside, coniferin, and to some other phenolic compounds. In addition to growth inhibition, Coniferyl alcohol caused the formation of a lignin-like compound detected by phloroglucinol staining in N. benthamiana roots and occasionally in BY-2 cells. To prevent this, we added potassium iodide (KI, at 5 mM) to overcome the peroxidase-mediated Coniferyl alcohol polymerization to lignin. KI had, however, toxic effects on its own: in N. benthamiana seedlings, it caused reduction in growth; in BY-2 cells, reduction in growth and cell viability. Surprisingly, Coniferyl alcohol restored the growth of KI-treated BY-2 cells and N. benthamiana seedlings.
CONCLUSIONS:
Our results suggest that Coniferyl alcohol at high concentrations is toxic to plant cells.

Coniferyl alcohol Dilution Calculator

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Coniferyl alcohol Molarity Calculator

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Preparing Stock Solutions of Coniferyl alcohol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.5494 mL 27.7469 mL 55.4939 mL 110.9878 mL 138.7347 mL
5 mM 1.1099 mL 5.5494 mL 11.0988 mL 22.1976 mL 27.7469 mL
10 mM 0.5549 mL 2.7747 mL 5.5494 mL 11.0988 mL 13.8735 mL
50 mM 0.111 mL 0.5549 mL 1.1099 mL 2.2198 mL 2.7747 mL
100 mM 0.0555 mL 0.2775 mL 0.5549 mL 1.1099 mL 1.3873 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Coniferyl alcohol

Coniferyl alcohol hinders the growth of tobacco BY-2 cells and Nicotiana benthamiana seedlings.[Pubmed:26108783]

Planta. 2015 Sep;242(3):747-60.

MAIN CONCLUSION: Externally added Coniferyl alcohol at high concentrations reduces the growth of Nicotiana cells and seedlings. Coniferyl alcohol is metabolized by BY-2 cells to several compounds. Coniferyl alcohol (CA) is a common monolignol and a building block of lignin. The toxicity of monolignol alcohols has been stated in the literature, but there are only few studies suggesting that this is true. We investigated the physiological effects of CA on living plant cells in more detail. Tobacco (Nicotiana tabacum) Bright yellow-2 cells (BY-2) and Nicotiana benthamiana seedlings both showed concentration-dependent growth retardation in response to 0.5-5 mM CA treatment. In some cases, CA addition caused cell death in BY-2 cultures, but this response was dependent on the growth stage of the cells. Based on LC-MS/MS analysis, BY-2 cells did not accumulate the externally supplemented CA, but metabolized it to ferulic acid, ferulic acid glycoside, coniferin, and to some other phenolic compounds. In addition to growth inhibition, CA caused the formation of a lignin-like compound detected by phloroglucinol staining in N. benthamiana roots and occasionally in BY-2 cells. To prevent this, we added potassium iodide (KI, at 5 mM) to overcome the peroxidase-mediated CA polymerization to lignin. KI had, however, toxic effects on its own: in N. benthamiana seedlings, it caused reduction in growth; in BY-2 cells, reduction in growth and cell viability. Surprisingly, CA restored the growth of KI-treated BY-2 cells and N. benthamiana seedlings. Our results suggest that CA at high concentrations is toxic to plant cells.

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