Crenulatin

CAS# 63026-02-8

Crenulatin

Catalog No. BCN7791----Order now to get a substantial discount!

Product Name & Size Price Stock
Crenulatin: 5mg $213 In Stock
Crenulatin: 10mg Please Inquire In Stock
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Quality Control of Crenulatin

Number of papers citing our products

Chemical structure

Crenulatin

3D structure

Chemical Properties of Crenulatin

Cas No. 63026-02-8 SDF Download SDF
PubChem ID 5316128 Appearance Powder
Formula C11H20O6 M.Wt 248.27
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(2-methylbut-3-en-2-yloxy)oxane-3,4,5-triol
SMILES CC(C)(C=C)OC1C(C(C(C(O1)CO)O)O)O
Standard InChIKey ZEGGZNOPAPRAIG-SPFKKGSWSA-N
Standard InChI InChI=1S/C11H20O6/c1-4-11(2,3)17-10-9(15)8(14)7(13)6(5-12)16-10/h4,6-10,12-15H,1,5H2,2-3H3/t6-,7-,8+,9-,10+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Crenulatin

The roots of Rhodiolae Crenulatae Radix et Rhizoma.

Biological Activity of Crenulatin

Description1. Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, inhibitive effect in 25 mg/L and stimulative effect in 100 mg/L group, respectively; the mechanism is related to the alterations of Fas/Bcl-2 expression and caspase-3 activity.
TargetsBcl-2/Bax | Caspase

Crenulatin Dilution Calculator

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Crenulatin Molarity Calculator

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Preparing Stock Solutions of Crenulatin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0279 mL 20.1394 mL 40.2787 mL 80.5575 mL 100.6968 mL
5 mM 0.8056 mL 4.0279 mL 8.0557 mL 16.1115 mL 20.1394 mL
10 mM 0.4028 mL 2.0139 mL 4.0279 mL 8.0557 mL 10.0697 mL
50 mM 0.0806 mL 0.4028 mL 0.8056 mL 1.6111 mL 2.0139 mL
100 mM 0.0403 mL 0.2014 mL 0.4028 mL 0.8056 mL 1.007 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Crenulatin

[Optimization of extraction technology for salidroside, tyrosol, crenulatin and gallic acid in Rhodiolae Crenulatae Radix et Rhizoma with orthogonal test].[Pubmed:26983205]

Zhongguo Zhong Yao Za Zhi. 2015 Sep;40(18):3590-3.

The extracting technology of salidroside, tyrosol, Crenulatin and gallic acid from Rhodiolae Crenulatae Radix et Rhizoma was optimized. With extraction rate of salidroside, tyrosol, Crenulatin and gallic acid as indexes, orthogonal test was used to evaluate effect of 4 factors on extracting technology, including concentration of solvent, the dosage of solvent, duration of extraction, and frequency of extraction. The results showed that, the best extracting technology was to extract in 70% alcohol with 8 times the weight of herbal medicine for 2 times, with 3 hours once. High extraction rate of salidroside, tyrosol, Crenulatin and gallic acid were obtained with the present technology. The extracting technology was stable and feasible with high extraction rate of four compounds from Rhodiolae Crenulatae Radix et Rhizoma, it was suitable for industrial production.

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