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Cytisine Hydrochloride

CAS# 6047-01-4

Cytisine Hydrochloride

Catalog No. BCN8133----Order now to get a substantial discount!

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Cytisine Hydrochloride: 5mg Please Inquire In Stock
Cytisine Hydrochloride: 10mg Please Inquire In Stock
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Quality Control of Cytisine Hydrochloride

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Chemical structure

Cytisine Hydrochloride

3D structure

Chemical Properties of Cytisine Hydrochloride

Cas No. 6047-01-4 SDF Download SDF
PubChem ID 20056518 Appearance Powder
Formula C11H15ClN2O M.Wt 226.70
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one;hydrochloride
SMILES C1C2CNCC1C3=CC=CC(=O)N3C2.Cl
Standard InChIKey NNYPHEBIGWBCNH-OULXEKPRSA-N
Standard InChI InChI=1S/C11H14N2O.ClH/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11;/h1-3,8-9,12H,4-7H2;1H/t8-,9+;/m0./s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cytisine Hydrochloride

The herb of Genista tinctoria L.

Biological Activity of Cytisine Hydrochloride

Description1. Cytisine hydrochloride has toxicity.

Cytisine Hydrochloride Dilution Calculator

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Cytisine Hydrochloride Molarity Calculator

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Preparing Stock Solutions of Cytisine Hydrochloride

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4111 mL 22.0556 mL 44.1112 mL 88.2223 mL 110.2779 mL
5 mM 0.8822 mL 4.4111 mL 8.8222 mL 17.6445 mL 22.0556 mL
10 mM 0.4411 mL 2.2056 mL 4.4111 mL 8.8222 mL 11.0278 mL
50 mM 0.0882 mL 0.4411 mL 0.8822 mL 1.7644 mL 2.2056 mL
100 mM 0.0441 mL 0.2206 mL 0.4411 mL 0.8822 mL 1.1028 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cytisine Hydrochloride

Some studies on cytisine and its methylated derivatives.[Pubmed:4387392]

Br J Pharmacol. 1969 Jan;35(1):161-74.

1. In mice Cytisine Hydrochloride is less toxic intravenously than nicotine hydrogen tartrate, but more toxic by intraperitoneal or oral administration. Compared with cytisine, caulophylline hydrogen iodide is one-fifth to one-tenth as toxic and caulophylline methiodide is less than one-thirtieth as toxic.2. The surprising low oral toxicity of cytisine and nicotine may be ascribed to the method of administration; if the drug is placed directly in the stomach there is no possibility of absorption through buccal mucous membranes.3. The peripheral effects of nicotine, cytisine and caulophylline are similar, though on some preparations those of nicotine last longer. In most tests cytisine is active in doses from a quarter to three-quarters of those of nicotine, caulophylline in doses from 10 to 20 times those of cytisine. Caulophylline methiodide is virtually inactive.4. Cytisine and caulophylline may differ from nicotine in their central effects.5. Cytisine and caulophylline are active as the cations. The pKa of cytisine is 7.92 and that of caulophylline is 7.04; the difference accounts, in part, for the weaker activity of caulophylline. The caulophylline ion is generally one-sixth to one-third as active as the cytisine ion.6. The introduction of the second methyl group to form the quaternary salt does not appear to cause a dramatic change in the conformation of the molecule. Caulophylline methiodide appears to be feebly active because it has feeble affinity.

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