ES 936

CAS# 192820-78-3

ES 936

Catalog No. BCC6102----Order now to get a substantial discount!

Product Name & Size Price Stock
ES 936: 5mg $115 In Stock
ES 936: 10mg Please Inquire In Stock
ES 936: 20mg Please Inquire Please Inquire
ES 936: 50mg Please Inquire Please Inquire
ES 936: 100mg Please Inquire Please Inquire
ES 936: 200mg Please Inquire Please Inquire
ES 936: 500mg Please Inquire Please Inquire
ES 936: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of ES 936

Number of papers citing our products

Chemical structure

ES 936

3D structure

Chemical Properties of ES 936

Cas No. 192820-78-3 SDF Download SDF
PubChem ID 4470790 Appearance Powder
Formula C18H16N2O6 M.Wt 356.33
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in DMSO > 10 mM
Chemical Name 5-methoxy-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4,7-dione
SMILES CC1=C(C2=C(N1C)C(=O)C=C(C2=O)OC)COC3=CC=C(C=C3)[N+](=O)[O-]
Standard InChIKey IBLWSLZYYZHSRG-UHFFFAOYSA-N
Standard InChI InChI=1S/C18H16N2O6/c1-10-13(9-26-12-6-4-11(5-7-12)20(23)24)16-17(19(10)2)14(21)8-15(25-3)18(16)22/h4-8H,9H2,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of ES 936

DescriptionMechanism-based inhibitor of NAD(P)H:quinone oxidoreductase (NQO1). Induces growth inhibition in human pancreatic carcinoma (MIA PaCa-2) and adenocarcinoma (BxPC-3) cell lines with IC50 values of 108 and 365 nM respectively. Also inhibits TNF-α-induced E-selectin protein expression in human bone marrow endothelial cells. Exhibits no effects on other cellular reductases or levels of acid-soluble thiols.

ES 936 Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

ES 936 Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of ES 936

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8064 mL 14.0319 mL 28.0639 mL 56.1277 mL 70.1597 mL
5 mM 0.5613 mL 2.8064 mL 5.6128 mL 11.2255 mL 14.0319 mL
10 mM 0.2806 mL 1.4032 mL 2.8064 mL 5.6128 mL 7.016 mL
50 mM 0.0561 mL 0.2806 mL 0.5613 mL 1.1226 mL 1.4032 mL
100 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.5613 mL 0.7016 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

Keywords:

ES 936,192820-78-3,Natural Products,Reductases, buy ES 936 , ES 936 supplier , purchase ES 936 , ES 936 cost , ES 936 manufacturer , order ES 936 , high purity ES 936

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: