Isodunnianol

CAS# 139726-30-0

Isodunnianol

Catalog No. BCN6213----Order now to get a substantial discount!

Product Name & Size Price Stock
Isodunnianol: 5mg $903 In Stock
Isodunnianol: 10mg Please Inquire In Stock
Isodunnianol: 20mg Please Inquire Please Inquire
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Isodunnianol: 500mg Please Inquire Please Inquire
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Quality Control of Isodunnianol

Number of papers citing our products

Chemical structure

Isodunnianol

3D structure

Chemical Properties of Isodunnianol

Cas No. 139726-30-0 SDF Download SDF
PubChem ID 15714606 Appearance Powder
Formula C27H26O3 M.Wt 398.5
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enyl-6-(4-prop-2-enylphenoxy)phenol
SMILES C=CCC1=CC=C(C=C1)OC2=C(C(=CC(=C2)CC=C)C3=C(C=CC(=C3)CC=C)O)O
Standard InChIKey HFHHTRIAKONNBG-UHFFFAOYSA-N
Standard InChI InChI=1S/C27H26O3/c1-4-7-19-10-13-22(14-11-19)30-26-18-21(9-6-3)17-24(27(26)29)23-16-20(8-5-2)12-15-25(23)28/h4-6,10-18,28-29H,1-3,7-9H2
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Isodunnianol

The fruits of Illicium fargesii

Biological Activity of Isodunnianol

Description1. Isodunnianol, dunnianol, and Macranthol have anti-inflammatory activity, they can increase NAG-1(multiple targets related to inflammation) activity 1.5 -3.0 fold and decrease cellular oxidative stress by 40-65%, they show substantial activity against iNOS. 2. Isodunnianol exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. 3. Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM.
TargetsNF-kB | NOS | ROS

Isodunnianol Dilution Calculator

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Isodunnianol Molarity Calculator

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Preparing Stock Solutions of Isodunnianol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5094 mL 12.5471 mL 25.0941 mL 50.1882 mL 62.7353 mL
5 mM 0.5019 mL 2.5094 mL 5.0188 mL 10.0376 mL 12.5471 mL
10 mM 0.2509 mL 1.2547 mL 2.5094 mL 5.0188 mL 6.2735 mL
50 mM 0.0502 mL 0.2509 mL 0.5019 mL 1.0038 mL 1.2547 mL
100 mM 0.0251 mL 0.1255 mL 0.2509 mL 0.5019 mL 0.6274 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Isodunnianol

Sesquilignans and sesquiterpenoid from the stem barks of Illicium simonsii and their anti-AChE activity

Natural Products and Bioprospecting June 2012, Volume 2, Issue 3, pp 133-137.

A biosynthetic pathway was proposed for simonsienols A-C (1–3). Anti-AChE activity and anti-BuChE activity were evaluated for all compounds except for α-cadinol ethyl ether (4). As a result, Isodunnianol (7) exhibited anti-AChE activity with an IC50 value of 13.0 µM.

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