Isopteleine

CAS# 2181-84-2

Isopteleine

Catalog No. BCN7067----Order now to get a substantial discount!

Product Name & Size Price Stock
Isopteleine: 5mg $799 In Stock
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Quality Control of Isopteleine

Number of papers citing our products

Chemical structure

Isopteleine

3D structure

Chemical Properties of Isopteleine

Cas No. 2181-84-2 SDF Download SDF
PubChem ID 776150 Appearance Powder
Formula C13H11NO3 M.Wt 229.23
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6-methoxy-9-methylfuro[2,3-b]quinolin-4-one
SMILES CN1C2=C(C=C(C=C2)OC)C(=O)C3=C1OC=C3
Standard InChIKey XKTZVOMYVJKQTH-UHFFFAOYSA-N
Standard InChI InChI=1S/C13H11NO3/c1-14-11-4-3-8(16-2)7-10(11)12(15)9-5-6-17-13(9)14/h3-7H,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Isopteleine

The roots of Dictamnus angustifolius G.Don ex Sweet .

Biological Activity of Isopteleine

Description1. Isopteleine shows weak cytotoxic activities against human breast cancer cells (MCF7).

Isopteleine Dilution Calculator

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Isopteleine Molarity Calculator

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Preparing Stock Solutions of Isopteleine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.3624 mL 21.8122 mL 43.6243 mL 87.2486 mL 109.0608 mL
5 mM 0.8725 mL 4.3624 mL 8.7249 mL 17.4497 mL 21.8122 mL
10 mM 0.4362 mL 2.1812 mL 4.3624 mL 8.7249 mL 10.9061 mL
50 mM 0.0872 mL 0.4362 mL 0.8725 mL 1.745 mL 2.1812 mL
100 mM 0.0436 mL 0.2181 mL 0.4362 mL 0.8725 mL 1.0906 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Isopteleine

A new quinoline alkaloid from the roots of Dictamnus angustifolius.[Pubmed:24702810]

Chin J Nat Med. 2014 Mar;12(3):222-4.

AIM: To investigate the quinoline alkaloids from the roots of Dictamnus angustifolius G.Don ex Sweet (Rutaceae). METHOD: The quinoline alkaloids were isolated by various column chromatographic methods and their structures were elucidated on the basis of spectral analysis. RESULTS: A new quinoline alkaloid, 5-methoxylrobustine (1), along with five known quinoline alkaloids were obtained, and their structures were identified as dictamnine (2), robustine (3), Isopteleine (4), gamma-fagarine (5), and skimmianine (6). Cytotoxicity testing of these alkaloids showed that all of them had weak cytotoxic activities against human breast cancer cells (MCF7). CONCLUSION: Compound 1 is a new quinoline alkaloid. Alkaloid 3 showed stronger anti-proliferation effect than the other alkaloids.

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