Lyclaninol

CAS# 53755-76-3

Lyclaninol

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Quality Control of Lyclaninol

Number of papers citing our products

Chemical structure

Lyclaninol

3D structure

Chemical Properties of Lyclaninol

Cas No. 53755-76-3 SDF Download SDF
PubChem ID 91895437 Appearance Powder
Formula C30H50O4 M.Wt 474.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1(C2CC=C3CC4(CCC5C(C4CCC3C2(CC(C1O)O)C)(CCC(C5(C)CO)O)C)C)C
Standard InChIKey MRQRSMCZZRLXJG-AGTZBQNOSA-N
Standard InChI InChI=1S/C30H50O4/c1-26(2)21-9-7-18-15-27(3)13-11-23-28(4,14-12-24(33)30(23,6)17-31)22(27)10-8-19(18)29(21,5)16-20(32)25(26)34/h7,19-25,31-34H,8-17H2,1-6H3/t19-,20+,21-,22-,23+,24+,25+,27-,28+,29+,30+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Lyclaninol

The herbs of Lycopodium serratum Thunb.

Biological Activity of Lyclaninol

DescriptionStandard reference

Protocol of Lyclaninol

Structure Identification
Yakugaku zasshi journal of the Pharmaceutical Society of Japan,1974, 94(8):970-90.

Chemotaxonomic studies on the triterpenoids of Lycopodium plants (Japanese)[Reference: WebLink]

Fifty-one samples of Lycopodium plants (mostly Japanese species), including 17 species and 3 varieties, were collected and their triterpenoid constituents were examined firstly by comparing microchemically and then characterized by isolating them after alkaline hydrolysis.
METHODS AND RESULTS:
Discussions are made on thin-layer chromatography and chemotaxonomy of lycopodium triterpenoids, isolation and characterization of triterpenoids constituents, relationship between location of growth and the constituents, and relationship between species and the constituents. All the plants examined contained triterpenoids of serratane group or its assumed precursor, α-onocerin, the former including 13 new triterpenoids, 16-oxoserratenediol, 16-oxo-21-episerratenediol, 16-oxodiepiserratenediol, 16-oxoserratriol, 16-oxolycoclavanol, lycocryptol, 21-epilycocryptol, diepilycocryptol, Lyclaninol, lyclanitin, 16-oxolyclanitin, lycernuic acid-A, and lycernuic acid-B, and two new glycosides of serratenediol and tohogenol. A new bisnortriterpenoid, clavatol, was isolated from L.clavatum. All these Lycopodium plants can be divided into three classes according to their major triterpenoids ; α-onocerin (L.clavatum, L.sitchense, L.obscurum, L.casuarinoides, L.inundatum), serratenediol (L.serratum, L.somae, L.cryptomerinum, L.chinense, L.sieboldii, L.fargesii, L.fordii, L.cernuum, L.phlegmaria), and 21-episerratriol (L.annotinum). Some of them (L.sitchense, L.annotinum, L.cernuum, and L.complanatum) showed variation in constituents depending on the locality of growth.
CONCLUSIONS:
Particularly, L.complanatum collected in Hokkaido contained α-onocerin as a major component, while the same plant from Taiwan did not contain α-onocerin but had 21-episerratriol as the major triterpenoid. Some plants of different species (cf. L.fargesii and L.fordii) were not distinguishable by their triterpenoid constituents suggesting their close relationship.

Lyclaninol Dilution Calculator

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Preparing Stock Solutions of Lyclaninol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1066 mL 10.533 mL 21.0659 mL 42.1319 mL 52.6648 mL
5 mM 0.4213 mL 2.1066 mL 4.2132 mL 8.4264 mL 10.533 mL
10 mM 0.2107 mL 1.0533 mL 2.1066 mL 4.2132 mL 5.2665 mL
50 mM 0.0421 mL 0.2107 mL 0.4213 mL 0.8426 mL 1.0533 mL
100 mM 0.0211 mL 0.1053 mL 0.2107 mL 0.4213 mL 0.5266 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Lyclaninol

Chemotaxonomic studies on the triterpenoids of Lycopodium plants (Japanese)

Yakugaku zasshi journal of the Pharmaceutical Society of Japan 94(8):970-90 · September 1974

Fifty-one samples of Lycopodium plants (mostly Japanese species), including 17 species and 3 varieties, were collected and their triterpenoid constituents were examined firstly by comparing microchemically and then characterized by isolating them after alkaline hydrolysis. Discussions are made on thin-layer chromatography and chemotaxonomy of lycopodium triterpenoids, isolation and characterization of triterpenoids constituents, relationship between location of growth and the constituents, and relationship between species and the constituents. All the plants examined contained triterpenoids of serratane group or its assumed precursor, α-onocerin, the former including 13 new triterpenoids, 16-oxoserratenediol, 16-oxo-21-episerratenediol, 16-oxodiepiserratenediol, 16-oxoserratriol, 16-oxolycoclavanol, lycocryptol, 21-epilycocryptol, diepilycocryptol, Lyclaninol, lyclanitin, 16-oxolyclanitin, lycernuic acid-A, and lycernuic acid-B, and two new glycosides of serratenediol and tohogenol. A new bisnortriterpenoid, clavatol, was isolated from L.clavatum. All these Lycopodium plants can be divided into three classes according to their major triterpenoids ; α-onocerin (L.clavatum, L.sitchense, L.obscurum, L.casuarinoides, L.inundatum), serratenediol (L.serratum, L.somae, L.cryptomerinum, L.chinense, L.sieboldii, L.fargesii, L.fordii, L.cernuum, L.phlegmaria), and 21-episerratriol (L.annotinum). Some of them (L.sitchense, L.annotinum, L.cernuum, and L.complanatum) showed variation in constituents depending on the locality of growth. Particularly, L.complanatum collected in Hokkaido contained α-onocerin as a major component, while the same plant from Taiwan did not contain α-onocerin but had 21-episerratriol as the major triterpenoid. Some plants of different species (cf. L.fargesii and L.fordii) were not distinguishable by their triterpenoid constituents suggesting their close relationship.

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