Home >> Research Area >>Natural Products>>Lignans>> Magnaldehyde D

Magnaldehyde D

CAS# 93753-33-4

Magnaldehyde D

Catalog No. BCN4070----Order now to get a substantial discount!

Product Name & Size Price Stock
Magnaldehyde D: 5mg $828 In Stock
Magnaldehyde D: 10mg Please Inquire In Stock
Magnaldehyde D: 20mg Please Inquire Please Inquire
Magnaldehyde D: 50mg Please Inquire Please Inquire
Magnaldehyde D: 100mg Please Inquire Please Inquire
Magnaldehyde D: 200mg Please Inquire Please Inquire
Magnaldehyde D: 500mg Please Inquire Please Inquire
Magnaldehyde D: 1000mg Please Inquire Please Inquire

Quality Control of Magnaldehyde D

Number of papers citing our products

Chemical structure

Magnaldehyde D

3D structure

Chemical Properties of Magnaldehyde D

Cas No. 93753-33-4 SDF Download SDF
PubChem ID 5319189 Appearance Powder
Formula C16H14O3 M.Wt 254.3
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-hydroxy-3-(2-hydroxy-5-prop-2-enylphenyl)benzaldehyde
SMILES C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)C=O)O
Standard InChIKey KDWYPRNOEMXUNA-UHFFFAOYSA-N
Standard InChI InChI=1S/C16H14O3/c1-2-3-11-4-6-15(18)13(8-11)14-9-12(10-17)5-7-16(14)19/h2,4-10,18-19H,1,3H2
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Magnaldehyde D

The barks of Magnolia officinalis

Biological Activity of Magnaldehyde D

DescriptionMagnaldehyde D is a natural product from Magnolia officinalis.
In vitro

New biphenyl derivatives and anti-inflammatory constituents from the stem bark of Magnolia officinalis[Reference: WebLink]

Planta Medica, 2011 , 77 (12):PG42.

The stem bark of Magnolia officinalis Rehd. et Wils. (Magnoliaceae) has been used as a traditional medicine for the treatment of gastrointestinal disorders, bronchitis, and emphysema, in China, Taiwan, Japan, and Korea [1]. Chemical studies have revealed a variety of neo-lignans and alkaloids as constituents of this plant. Many of these compounds exhibit central depressant effect, muscle relaxation, and antigastric ulcer, antibacterial, antiallergic, vasorelaxant, and neurotrophic activities.
METHODS AND RESULTS:
Investigation on EtOAc-soluble fraction of the stem bark of M. officinalis has led to the isolation of three new biphenyls, 5-allyl-5'-(1-hydroxyallyloxy)biphenyl-2,2-diol (1), 5,5'-diallyl-2'-(allyloxy)biphenyl-2-ol (2), and 5,5'-diallyl-2'-(3-methylbut-2-enyloxy)biphenyl-2-ol (3), together with 12 known compounds, including four neolignans, magnolol (4), honokiol (5), (-)-monoterpenylmagnolol (6), and randainal (7), two norlignans, Magnaldehyde D (8) and randaiol (9), and six steroids, β-sitostenone (10), stigmasta-4,22-dien-3-one (11), β-sitosterol (12), stigmasterol (13), 3β-hydroxystigmast-5-en-7-one (14), and 3β-hydroxystigmasta-5,22-dien-7-one (15).
CONCLUSIONS:
The structure of new compounds (1-3) were determined through spectroscopic and MS analyses. Among the isolates, magnolol (4) and honokiol (5) exhibited potent inhibition against fMLP-induced superoxide production with IC50 values of 4.42±0.24 and 0.68±0.20μg/mL, respectively. In addition, magnolol (4) inhibited fMLP/CB-induced elastase release with an IC50 values of 1.45±0.20μg/mL.

Protocol of Magnaldehyde D

Structure Identification
Magn Reson Chem. 2008 May;46(5):497-500.

1H and 13C NMR assignments for two lignans from the heartwood of Streblus asper.[Pubmed: 18297743 ]


METHODS AND RESULTS:
In our ongoing investigation of the bioactive constituents from plants, two new lignans, magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol were isolated from heartwood of Streblus asper, along with three known lignans, magnolignan A, magnolol, and Magnaldehyde D. 1D and 2D NMR experiments, including COSY, HMQC, and HMBC, and other spectroscopic methods, including UV, IR, and MS were used for the determination of the structures and NMR assignments.
CONCLUSIONS:
Primary bioassays showed that magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol have medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, 46.4 microM and 10.1 microM, 21.7 microM, respectively.

Magnaldehyde D Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Magnaldehyde D Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Magnaldehyde D

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.9324 mL 19.6618 mL 39.3236 mL 78.6473 mL 98.3091 mL
5 mM 0.7865 mL 3.9324 mL 7.8647 mL 15.7295 mL 19.6618 mL
10 mM 0.3932 mL 1.9662 mL 3.9324 mL 7.8647 mL 9.8309 mL
50 mM 0.0786 mL 0.3932 mL 0.7865 mL 1.5729 mL 1.9662 mL
100 mM 0.0393 mL 0.1966 mL 0.3932 mL 0.7865 mL 0.9831 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Magnaldehyde D

1H and 13C NMR assignments for two lignans from the heartwood of Streblus asper.[Pubmed:18297743]

Magn Reson Chem. 2008 May;46(5):497-500.

In our ongoing investigation of the bioactive constituents from plants, two new lignans, magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol were isolated from heartwood of Streblus asper, along with three known lignans, magnolignan A, magnolol, and Magnaldehyde D. 1D and 2D NMR experiments, including COSY, HMQC, and HMBC, and other spectroscopic methods, including UV, IR, and MS were used for the determination of the structures and NMR assignments. Primary bioassays showed that magnolignan A-2-O-beta-D-glucopyranoside and strebluslignanol have medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, 46.4 microM and 10.1 microM, 21.7 microM, respectively.

Keywords:

Magnaldehyde D,93753-33-4,Natural Products, buy Magnaldehyde D , Magnaldehyde D supplier , purchase Magnaldehyde D , Magnaldehyde D cost , Magnaldehyde D manufacturer , order Magnaldehyde D , high purity Magnaldehyde D

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: