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Mulberroside F

CAS# 193483-95-3

Mulberroside F

Catalog No. BCN2908----Order now to get a substantial discount!

Product Name & Size Price Stock
Mulberroside F: 5mg $161 In Stock
Mulberroside F: 10mg Please Inquire In Stock
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Quality Control of Mulberroside F

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Chemical structure

Mulberroside F

3D structure

Chemical Properties of Mulberroside F

Cas No. 193483-95-3 SDF Download SDF
PubChem ID 60208818 Appearance Powder
Formula C26H30O14 M.Wt 566.5
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[2-[3-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1-benzofuran-6-yl]oxy]oxane-3,4,5-triol
SMILES C1=CC2=C(C=C1OC3C(C(C(C(O3)CO)O)O)O)OC(=C2)C4=CC(=CC(=C4)OC5C(C(C(C(O5)CO)O)O)O)O
Standard InChIKey YPMOTUXWPXDQDJ-PCIRLDFKSA-N
Standard InChI InChI=1S/C26H30O14/c27-8-17-19(30)21(32)23(34)25(39-17)36-13-2-1-10-5-15(38-16(10)7-13)11-3-12(29)6-14(4-11)37-26-24(35)22(33)20(31)18(9-28)40-26/h1-7,17-35H,8-9H2/t17-,18-,19-,20-,21+,22+,23-,24-,25-,26-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Mulberroside F

The root barks of Morus alba L.

Biological Activity of Mulberroside F

DescriptionMulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells, it also exhibits superoxide scavenging activity that is involved in the protection against auto-oxidation, suggests that mulberroside F may be used as a skin whitening agent.
TargetsTyrosinase
In vitro

Mulberroside F isolated from the leaves of Morus alba inhibits melanin biosynthesis.[Pubmed: 12186407]

Biol Pharm Bull. 2002 Aug;25(8):1045-8.


METHODS AND RESULTS:
The current study was carried out to investigate the in vitro effects of an 85% methanol extract of dried Morus alba leaves on melanin biosynthesis, which is closely related to hyperpigmentation. These extracts inhibited the tyrosinase activity that converts dopa to dopachrome in the biosynthetic process of melanin. Mulberroside F (moracin M-6, 3'-di-O-beta-D-glucopyranoside), which was obtained after the bioactivity-guided fractionation of the extracts, showed inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells. This compound also exhibited superoxide scavenging activity that is involved in the protection against auto-oxidation. But its activity was low and was weaker than of kojic acid.
CONCLUSIONS:
These results suggest that Mulberroside F isolated from mulberry leaves might be used as a skin whitening agent.

Mulberroside F Dilution Calculator

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Mulberroside F Molarity Calculator

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Preparing Stock Solutions of Mulberroside F

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7652 mL 8.8261 mL 17.6523 mL 35.3045 mL 44.1306 mL
5 mM 0.353 mL 1.7652 mL 3.5305 mL 7.0609 mL 8.8261 mL
10 mM 0.1765 mL 0.8826 mL 1.7652 mL 3.5305 mL 4.4131 mL
50 mM 0.0353 mL 0.1765 mL 0.353 mL 0.7061 mL 0.8826 mL
100 mM 0.0177 mL 0.0883 mL 0.1765 mL 0.353 mL 0.4413 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Mulberroside F

Mulberroside F isolated from the leaves of Morus alba inhibits melanin biosynthesis.[Pubmed:12186407]

Biol Pharm Bull. 2002 Aug;25(8):1045-8.

The current study was carried out to investigate the in vitro effects of an 85% methanol extract of dried Morus alba leaves on melanin biosynthesis, which is closely related to hyperpigmentation. These extracts inhibited the tyrosinase activity that converts dopa to dopachrome in the biosynthetic process of melanin. Mulberroside F (moracin M-6, 3'-di-O-beta-D-glucopyranoside), which was obtained after the bioactivity-guided fractionation of the extracts, showed inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells. This compound also exhibited superoxide scavenging activity that is involved in the protection against auto-oxidation. But its activity was low and was weaker than of kojic acid. These results suggest that Mulberroside F isolated from mulberry leaves might be used as a skin whitening agent.

Description

Mulberroside F is one of the main bioactive constituents in mulberry (Morus alba L.). Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation. Mulberroside F also exhibits superoxide scavenging activity that is involved in the protection against auto-oxidation.

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