Home >> Research Area >>Natural Products>>Chalcones>> Pinostrobin chalcone

Pinostrobin chalcone

CAS# 18956-15-5

Pinostrobin chalcone

Catalog No. BCN1173----Order now to get a substantial discount!

Product Name & Size Price Stock
Pinostrobin chalcone: 5mg Please Inquire In Stock
Pinostrobin chalcone: 10mg Please Inquire In Stock
Pinostrobin chalcone: 20mg Please Inquire Please Inquire
Pinostrobin chalcone: 50mg Please Inquire Please Inquire
Pinostrobin chalcone: 100mg Please Inquire Please Inquire
Pinostrobin chalcone: 200mg Please Inquire Please Inquire
Pinostrobin chalcone: 500mg Please Inquire Please Inquire
Pinostrobin chalcone: 1000mg Please Inquire Please Inquire

Quality Control of Pinostrobin chalcone

Number of papers citing our products

Chemical structure

Pinostrobin chalcone

3D structure

Chemical Properties of Pinostrobin chalcone

Cas No. 18956-15-5 SDF Download SDF
PubChem ID 5316793 Appearance Yellow-orange powder
Formula C16H14O4 M.Wt 270.3
Type of Compound Chalcones Storage Desiccate at -20°C
Synonyms Pinostrobin chalcone
Solubility Soluble in chloroform and methan
Chemical Name (E)-1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one
SMILES COC1=CC(=C(C(=C1)O)C(=O)C=CC2=CC=CC=C2)O
Standard InChIKey CUGDOWNTXKLQMD-BQYQJAHWSA-N
Standard InChI InChI=1S/C16H14O4/c1-20-12-9-14(18)16(15(19)10-12)13(17)8-7-11-5-3-2-4-6-11/h2-10,18-19H,1H3/b8-7+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pinostrobin chalcone

The heartwoods of Lindera umbellata.

Biological Activity of Pinostrobin chalcone

Description1. Pinostrobin chalcone displays very remarkable cytotoxic activity against the human cancer cells, such as KB, MCF7 and Caski cells (IC50 values of 6.2, 7.3 and 7.7 ug/mL, respectively). 2. Pinostrobin chalcone is a potent inhibitor of triglyceride accumulation, it can inhibit adipogenesis in 3T3-L1 cells, it may have anti-obesity effects through the inhibition of adipogenesis.
TargetsFatty Acid Synthase

Pinostrobin chalcone Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Pinostrobin chalcone Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Pinostrobin chalcone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6996 mL 18.498 mL 36.9959 mL 73.9919 mL 92.4898 mL
5 mM 0.7399 mL 3.6996 mL 7.3992 mL 14.7984 mL 18.498 mL
10 mM 0.37 mL 1.8498 mL 3.6996 mL 7.3992 mL 9.249 mL
50 mM 0.074 mL 0.37 mL 0.7399 mL 1.4798 mL 1.8498 mL
100 mM 0.037 mL 0.185 mL 0.37 mL 0.7399 mL 0.9249 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Pinostrobin chalcone

Phytochemical and cytotoxic investigations of Alpinia mutica rhizomes.[Pubmed:21240148]

Molecules. 2011 Jan 14;16(1):583-9.

The methanol and fractionated extracts (hexane, ethyl acetate and water) of Alpinia mutica (Zingiberaceae) rhizomes were investigated for their cytotoxic effect against six human carcinoma cell lines, namely KB, MCF7, A549, Caski, HCT116, HT29 and non-human fibroblast cell line (MRC 5) using an in vitro cytotoxicity assay. The ethyl acetate extract possessed high inhibitory effect against KB, MCF7 and Caski cells (IC(5)(0) values of 9.4, 19.7 and 19.8 microg/mL, respectively). Flavokawin B (1), 5,6-dehydrokawain (2), Pinostrobin chalcone (3) and alpinetin (4), isolated from the active ethyl acetate extract were also evaluated for their cytotoxic activity. Of these, Pinostrobin chalcone (3) and alpinetin (4) were isolated from this plant for the first time. Pinostrobin chalcone (3) displayed very remarkable cytotoxic activity against the tested human cancer cells, such as KB, MCF7 and Caski cells (IC(5)(0) values of 6.2, 7.3 and 7.7 microg/mL, respectively). This is the first report of the cytotoxic activity of Alpinia mutica.

Keywords:

Pinostrobin chalcone,18956-15-5,Pinostrobin chalcone,Natural Products, buy Pinostrobin chalcone , Pinostrobin chalcone supplier , purchase Pinostrobin chalcone , Pinostrobin chalcone cost , Pinostrobin chalcone manufacturer , order Pinostrobin chalcone , high purity Pinostrobin chalcone

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: