Pyrrolam B

CAS# 126424-77-9

Pyrrolam B

Catalog No. BCN1986----Order now to get a substantial discount!

Product Name & Size Price Stock
Pyrrolam B: 5mg Please Inquire In Stock
Pyrrolam B: 10mg Please Inquire In Stock
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Quality Control of Pyrrolam B

Number of papers citing our products

Chemical structure

Pyrrolam B

3D structure

Chemical Properties of Pyrrolam B

Cas No. 126424-77-9 SDF Download SDF
PubChem ID 134715011 Appearance Powder
Formula C8H13NO2 M.Wt 155.20
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (8S)-8-methoxy-2,5,6,7-tetrahydro-1H-pyrrolizin-3-one
SMILES COC12CCCN1C(=O)CC2
Standard InChIKey GDAIAQLKZOBITI-QMMMGPOBSA-N
Standard InChI InChI=1S/C8H13NO2/c1-11-8-4-2-6-9(8)7(10)3-5-8/h2-6H2,1H3/t8-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pyrrolam B

The Streptomyces olivaceus

Biological Activity of Pyrrolam B

DescriptionPyrrolam B is a natural product from Streptomyces olivaceus.

Protocol of Pyrrolam B

Structure Identification
Author version: Synthesis, 2012,44; 2373-2681.

Pyrrolizidine Alkaloids Pyrrolams A-D: Survey on Synthetic Efforts, Biological Activities, and Studies on their Stability[Reference: WebLink]

Pyrrolam A is a microbial metabolite, structurally related to plant alkaloids of the necine-type, and was isolated from the bacterial strain of Streptomyces olivaceus along with the related alkaloids Pyrrolam B, pyrrolam C, and pyrrolam D .
METHODS AND RESULTS:
The synthesis of (S)- and (R)-pyrrolam A has attracted the attention of chemists in recent years, with 10 syntheses reported to date. The reported routes utilize the advantages of chiral proline as a starting material, with pyrrolidine nucleus as source of one of the two rings on which the second ring has been constructed.
CONCLUSIONS:
This review discusses the isolation of the deceptively simple pyrrolizidine alkaloid pyrrolam A, its biological studies, synthesis, and computational studies on the stability of the double bond in its strained bicyclic skeleton. In addition, the synthesis of pyrrolams B-C and their relationship to pyrrolam A is also discussed.

Pyrrolam B Dilution Calculator

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Pyrrolam B Molarity Calculator

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Preparing Stock Solutions of Pyrrolam B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.4433 mL 32.2165 mL 64.433 mL 128.866 mL 161.0825 mL
5 mM 1.2887 mL 6.4433 mL 12.8866 mL 25.7732 mL 32.2165 mL
10 mM 0.6443 mL 3.2216 mL 6.4433 mL 12.8866 mL 16.1082 mL
50 mM 0.1289 mL 0.6443 mL 1.2887 mL 2.5773 mL 3.2216 mL
100 mM 0.0644 mL 0.3222 mL 0.6443 mL 1.2887 mL 1.6108 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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