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Tetraethylenepentamine 5HCl

CAS# 4961-41-5

Tetraethylenepentamine 5HCl

Catalog No. BCC3867----Order now to get a substantial discount!

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Chemical structure

Tetraethylenepentamine 5HCl

3D structure

Chemical Properties of Tetraethylenepentamine 5HCl

Cas No. 4961-41-5 SDF Download SDF
PubChem ID 10309252 Appearance Powder
Formula C8H28Cl5N5 M.Wt 371.61
Type of Compound N/A Storage Desiccate at -20°C
Solubility <3.72mg/mL in DMSO
Chemical Name N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine;pentahydrochloride
SMILES C(CNCCNCCNCCN)N.Cl.Cl.Cl.Cl.Cl
Standard InChIKey VGICAQBLDJAGSJ-UHFFFAOYSA-N
Standard InChI InChI=1S/C8H23N5.5ClH/c9-1-3-11-5-7-13-8-6-12-4-2-10;;;;;/h11-13H,1-10H2;5*1H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Tetraethylenepentamine 5HCl Dilution Calculator

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Tetraethylenepentamine 5HCl Molarity Calculator

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Preparing Stock Solutions of Tetraethylenepentamine 5HCl

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.691 mL 13.455 mL 26.9099 mL 53.8199 mL 67.2748 mL
5 mM 0.5382 mL 2.691 mL 5.382 mL 10.764 mL 13.455 mL
10 mM 0.2691 mL 1.3455 mL 2.691 mL 5.382 mL 6.7275 mL
50 mM 0.0538 mL 0.2691 mL 0.5382 mL 1.0764 mL 1.3455 mL
100 mM 0.0269 mL 0.1345 mL 0.2691 mL 0.5382 mL 0.6727 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Tetraethylenepentamine 5HCl

Effects of some chelating agents on urinary copper excretion by the rat.[Pubmed:8555409]

Chem Res Toxicol. 1995 Oct-Nov;8(7):942-8.

In order to estimate the potential advantages of new chelating agents which can enhance copper excretion in the chronic copper intoxication arising in Wilson's disease, the relative ability of none chelating agents to induce the urinary excretion of copper was compared with that of D-penicillamine (DPA) and triethylenetetramine.2HCl (TRIEN), all given ip at 1 mmol/kg to male Sprague-Dawley rats. The compounds examined were as follows: tris(2-aminoethyl)-amine.3HCl (TREN), tetraethylenepentamine.5HCl (TETREN), pentaethylenehexamine.6HCl (PENTEN), 1,4,7,11-tetraazaundecane.4HCl (TAUD), 1,5,8,12-tetraazadodecane.4HCl (TADD), 1-N-benzyltriethylenetetramine.4HCl (BzTT), 4,7,10,13-tetraazatridecanoic acid.2H2SO4 (TTPA), 1,10-bis(2-pyridylmethyl)-1,4,7,10-tetraazadecane.4HCl (BPTETA), and N,N-bis(2-pyridylmethyl)-4-(aminomethyl)benzoic acid (4ABA). Of these, BzTT, TTPA, and 4ABA are new chelating agents not previously reported. The factors by which these chelating agents enhanced copper excretion over control (untreated) levels were as follows: DPA, 7.2; TREN, 1.6; TRIEN, 4.0; TETREN, 10.1; PENTEN, 7.8; TAUD, 7.8; TADD, 2.6; TTPA, 5.6; BzTT, 1.8; and 4ABA, 5.5. The results indicate that it may well be possible to develop additional chelating agents which are equal or superior to those now used in the treatment of Wilson's disease, as well as structural types whose immunological properties may be significantly different from DPA or TRIEN, the compounds currently used in the clinic for this disorder.

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