Z-Val-OH

CAS# 1149-26-4

Z-Val-OH

Catalog No. BCC2734----Order now to get a substantial discount!

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Chemical structure

Z-Val-OH

3D structure

Chemical Properties of Z-Val-OH

Cas No. 1149-26-4 SDF Download SDF
PubChem ID 6925692 Appearance Powder
Formula C13H17NO4 M.Wt 251.3
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate
SMILES CC(C)C(C(=O)[O-])NC(=O)OCC1=CC=CC=C1
Standard InChIKey CANZBRDGRHNSGZ-LLVKDONJSA-M
Standard InChI InChI=1S/C13H17NO4/c1-9(2)11(12(15)16)14-13(17)18-8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3,(H,14,17)(H,15,16)/p-1/t11-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Z-Val-OH Dilution Calculator

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Z-Val-OH Molarity Calculator

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Preparing Stock Solutions of Z-Val-OH

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.9793 mL 19.8965 mL 39.7931 mL 79.5862 mL 99.4827 mL
5 mM 0.7959 mL 3.9793 mL 7.9586 mL 15.9172 mL 19.8965 mL
10 mM 0.3979 mL 1.9897 mL 3.9793 mL 7.9586 mL 9.9483 mL
50 mM 0.0796 mL 0.3979 mL 0.7959 mL 1.5917 mL 1.9897 mL
100 mM 0.0398 mL 0.199 mL 0.3979 mL 0.7959 mL 0.9948 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Z-Val-OH

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References on Z-Val-OH

Solution synthesis of the glyco-hexapeptide sequence of the human oncofetal fibronectin defined by monoclonal antibody FDC-6.[Pubmed:1724973]

Int J Pept Protein Res. 1991 Nov;38(5):417-27.

The glyco-hexapeptide sequence H-Val-(GalNAc-alpha)Thr-His-Pro-Gly-Tyr-OH, was synthesized in solution by the segment condensation procedure and the stepwise procedure. A peracetylated, O-galactosaminyl threonine derivative was used for incorporating the glycosylated amino acid residue into the peptide chain. A consistent racemization occurred during the acylation of H-His-Pro-Gly-Tyr(Bzl)-OBzl with Z-Val-[GalNAc(Ac)3-alpha]Thr-OH by the BOP-HOBt procedure and the D-allothreonine containing glyco-hexapeptide was isolated in about 20% yield. Stepwise elongation of the C-terminal tetrapeptide with Fmoc-[GalNAc(Ac)3-alpha]Thr-OH and Z-Val-OH, in the presence of the same coupling reagents, yielded the L-threonine containing diastereoisomer without detectable racemization. A side product, the Nim-ethoxycarbonylated hexapeptide derivative, formed during the EEDQ-mediated condensation of Fmoc-[GalNAc(Ac)3-alpha]Thr-OH with the C-terminal tetrapeptide, was isolated and characterized. Preliminary studies showed that the synthetic glycohexapeptide is a good competitive inhibitor of the binding of the FDC-6 monoclonal antibody to the oncofetal fibronectin, supporting the idea that it should represent the minimum essential structure required for the FDC-6 activity.

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