FGF-basic 147 (FGF2), Recombinant ProteinCatalog# BCP33897 |
| Product Name | FGF-basic 147 (FGF2), Recombinant Protein | ||
| Full Product Name | FGF-basic 147, human recombinant | ||
| Product Synonym Names | FGF2; HBGF-2; Prostatropin; Basic fibroblast growth factor; Heparin-binding growth factor 2; FGFB | ||
| Product Gene Name | FGF2 recombinant protein | ||
| Research Use Only | For Research Use Only. Not for use in diagnostic procedures. | ||
| Sequence | MPALPEDGGS GAFPPGHFKD PKRLYCKNGG FFLRIHPDGR VDGVREKSDP HIKLQLQAEE RGVVSIKGVC ANRYLAMKED GRLLASKCVT DECFFFERLE SNNYNTYRSR KYTSWYVALK RTGQYKLGSK TGPGQKAILF LPMSAKS | ||
| OMIM | 134920 | ||
| 3D Structure | ModBase 3D Structure for P09038 | ||
| Host | E Coli | ||
| Purity/Purification | >=97% | ||
| Form/Format | Lyophilized from a 10 mM Na2PO4, pH 8.0. Appearance: Lyophilized protein | ||
| Solubility/Reconstitution Instructions | Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions. | ||
| Endotoxin Level | <0.01 ng/mug | ||
| Biological Activity | EC50 is typically 0.67-1.45 ng/ml. The activity was determined by the dose-dependent stimulation of mouse BALB/c 3T3 cells. | ||
| Results | 0.67-1.45 ng/ml | ||
| Handling | Centrifuge the vial prior to opening. | ||
| Preparation and Storage | At -20 degree CShelf Life: 12 months | ||
| Other Notes | Small volumes of FGF2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. | ||
| Related Product Information for FGF2 recombinant protein | Background: Fibroblast Growth Factors, FGFs, are a 22 member family of proteins known to be involved in angiogenesis, wound healing and embryonic development. As a family, they bind to heparin and signal through four receptor tyrosine kinases called, FGFR1, 2, 3 and 4. Although the mechanism remains unclear, FGF-basic 147 (variant of FGF basic 154) is a critical component in keeping embryonic stem cells undifferentiated in cell culture systems. Recombinant human FGF-b 147 (FGF-2) is a non-glycosylated protein, containing 147 amino acids, and having a molecular mass of 16.5 kDa. | ||
| Product Categories/Family for FGF2 recombinant protein | Proteins and Enzymes; Cytokines, Growth Factors & Hormones; FGFsProteins and Enzymes; Cytokines, Growth Factors & Hormones; Cytokines & Growth Factors (A-Z)Proteins and Enzymes; Proteins and Enzymes (A-Z)Proteins and Enzymes; Animal-Free Origin (AOF) Reco | ||
| Applications Tested/Suitable for FGF2 recombinant protein | SDS-PAGE; HPLC | ||
| NCBI GI # | 153285461 | ||
| NCBI GeneID | 2247 | ||
| NCBI Accession # | NP_001997.5 | ||
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