Home >> Research Area >>Neuroscience>>GluR>> (RS)-4-Carboxy-3-hydroxyphenylglycine

(RS)-4-Carboxy-3-hydroxyphenylglycine

Broad spectrum EAA ligand CAS# 134052-66-7

(RS)-4-Carboxy-3-hydroxyphenylglycine

Catalog No. BCC6598----Order now to get a substantial discount!

Product Name & Size Price Stock
(RS)-4-Carboxy-3-hydroxyphenylglycine: 5mg $115 In Stock
(RS)-4-Carboxy-3-hydroxyphenylglycine: 10mg Please Inquire In Stock
(RS)-4-Carboxy-3-hydroxyphenylglycine: 20mg Please Inquire Please Inquire
(RS)-4-Carboxy-3-hydroxyphenylglycine: 50mg Please Inquire Please Inquire
(RS)-4-Carboxy-3-hydroxyphenylglycine: 100mg Please Inquire Please Inquire
(RS)-4-Carboxy-3-hydroxyphenylglycine: 200mg Please Inquire Please Inquire
(RS)-4-Carboxy-3-hydroxyphenylglycine: 500mg Please Inquire Please Inquire
(RS)-4-Carboxy-3-hydroxyphenylglycine: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of (RS)-4-Carboxy-3-hydroxyphenylglycine

Number of papers citing our products

Chemical structure

(RS)-4-Carboxy-3-hydroxyphenylglycine

3D structure

Chemical Properties of (RS)-4-Carboxy-3-hydroxyphenylglycine

Cas No. 134052-66-7 SDF Download SDF
PubChem ID 1297 Appearance Powder
Formula C9H9NO5 M.Wt 211.17
Type of Compound N/A Storage Desiccate at -20°C
Synonyms (<em>RS</em>)-4C3HPG
Solubility Soluble to 100 mM in 1eq. NaOH
Chemical Name 4-[amino(carboxy)methyl]-2-hydroxybenzoic acid
SMILES C1=CC(=C(C=C1C(C(=O)O)N)O)C(=O)O
Standard InChIKey GXZSAQLJWLCLOX-UHFFFAOYSA-N
Standard InChI InChI=1S/C9H9NO5/c10-7(9(14)15)4-1-2-5(8(12)13)6(11)3-4/h1-3,7,11H,10H2,(H,12,13)(H,14,15)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of (RS)-4-Carboxy-3-hydroxyphenylglycine

DescriptionBroad spectrum EAA agonist/antagonist. Separate isomer (S)-4-Carboxy-3-hydroxyphenylglycine also available.

(RS)-4-Carboxy-3-hydroxyphenylglycine Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

(RS)-4-Carboxy-3-hydroxyphenylglycine Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of (RS)-4-Carboxy-3-hydroxyphenylglycine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7355 mL 23.6776 mL 47.3552 mL 94.7104 mL 118.388 mL
5 mM 0.9471 mL 4.7355 mL 9.471 mL 18.9421 mL 23.6776 mL
10 mM 0.4736 mL 2.3678 mL 4.7355 mL 9.471 mL 11.8388 mL
50 mM 0.0947 mL 0.4736 mL 0.9471 mL 1.8942 mL 2.3678 mL
100 mM 0.0474 mL 0.2368 mL 0.4736 mL 0.9471 mL 1.1839 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on (RS)-4-Carboxy-3-hydroxyphenylglycine

4C3HPG (RS-4-carboxy-3-hydroxyphenylglycine), a weak agonist at metabotropic glutamate receptors, occludes the action of trans-ACPD in hippocampus.[Pubmed:1385184]

Eur J Pharmacol. 1992 Oct 20;221(2-3):401-2.

The determination of the physiological role of glutamatergic metabotropic actions has been hampered by the lack of potent and specific antagonists. It has recently been reported that 4C3HPG (RS-4-carboxy-3-hydroxyphenylglycine) can antagonize metabotropic responses in the central nervous system. The effects of 4C3HPG on metabotropic responses evoked by trans-ACPD were investigated in CA3 pyramidal cells in hippocampal slice cultures. Our results show that in hippocampus 4C3HPG fails to antagonize responses mediated by metabotropic glutamate receptors.

Keywords:

(RS)-4-Carboxy-3-hydroxyphenylglycine,134052-66-7,(<em>RS</em>)-4C3HPG,Natural Products,GluR, buy (RS)-4-Carboxy-3-hydroxyphenylglycine , (RS)-4-Carboxy-3-hydroxyphenylglycine supplier , purchase (RS)-4-Carboxy-3-hydroxyphenylglycine , (RS)-4-Carboxy-3-hydroxyphenylglycine cost , (RS)-4-Carboxy-3-hydroxyphenylglycine manufacturer , order (RS)-4-Carboxy-3-hydroxyphenylglycine , high purity (RS)-4-Carboxy-3-hydroxyphenylglycine

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: