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2,3-DCPE hydrochloride

Bcl-XL protein expression downregulator CAS# 418788-90-6

2,3-DCPE hydrochloride

Catalog No. BCC2384----Order now to get a substantial discount!

Product Name & Size Price Stock
2,3-DCPE hydrochloride: 5mg $58 In Stock
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Chemical structure

2,3-DCPE hydrochloride

3D structure

Chemical Properties of 2,3-DCPE hydrochloride

Cas No. 418788-90-6 SDF Download SDF
PubChem ID 2250974 Appearance Powder
Formula C11H16Cl2NO2+ M.Wt 265.2
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble to 100 mM in sterile water
Chemical Name 3-(2,3-dichlorophenoxy)propyl-(2-hydroxyethyl)azanium
SMILES C1=CC(=C(C(=C1)Cl)Cl)OCCC[NH2+]CCO
Standard InChIKey QVEIRCZEBQRCTR-UHFFFAOYSA-O
Standard InChI InChI=1S/C11H15Cl2NO2/c12-9-3-1-4-10(11(9)13)16-8-2-5-14-6-7-15/h1,3-4,14-15H,2,5-8H2/p+1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

2,3-DCPE hydrochloride Dilution Calculator

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2,3-DCPE hydrochloride Molarity Calculator

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Preparing Stock Solutions of 2,3-DCPE hydrochloride

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7707 mL 18.8537 mL 37.7074 mL 75.4148 mL 94.2685 mL
5 mM 0.7541 mL 3.7707 mL 7.5415 mL 15.083 mL 18.8537 mL
10 mM 0.3771 mL 1.8854 mL 3.7707 mL 7.5415 mL 9.4268 mL
50 mM 0.0754 mL 0.3771 mL 0.7541 mL 1.5083 mL 1.8854 mL
100 mM 0.0377 mL 0.1885 mL 0.3771 mL 0.7541 mL 0.9427 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on 2,3-DCPE hydrochloride

Selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro. IC50 values are 0.89 and 12.6 μM for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways.

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