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7',8'-Dihydroobolactone

CAS# 1240403-82-0

7',8'-Dihydroobolactone

Catalog No. BCN7196----Order now to get a substantial discount!

Product Name & Size Price Stock
7',8'-Dihydroobolactone: 5mg $886 In Stock
7',8'-Dihydroobolactone: 10mg Please Inquire In Stock
7',8'-Dihydroobolactone: 20mg Please Inquire Please Inquire
7',8'-Dihydroobolactone: 50mg Please Inquire Please Inquire
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7',8'-Dihydroobolactone: 200mg Please Inquire Please Inquire
7',8'-Dihydroobolactone: 500mg Please Inquire Please Inquire
7',8'-Dihydroobolactone: 1000mg Please Inquire Please Inquire

Quality Control of 7',8'-Dihydroobolactone

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Chemical structure

7',8'-Dihydroobolactone

3D structure

Chemical Properties of 7',8'-Dihydroobolactone

Cas No. 1240403-82-0 SDF Download SDF
PubChem ID 46911676 Appearance Oil
Formula C19H20O4 M.Wt 312.36
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R)-2-[[(2R)-6-oxo-2,3-dihydropyran-2-yl]methyl]-6-(2-phenylethyl)-2,3-dihydropyran-4-one
SMILES C1C=CC(=O)OC1CC2CC(=O)C=C(O2)CCC3=CC=CC=C3
Standard InChIKey GLFJXECVUDGKBE-AEFFLSMTSA-N
Standard InChI InChI=1S/C19H20O4/c20-15-11-17(10-9-14-5-2-1-3-6-14)22-18(12-15)13-16-7-4-8-19(21)23-16/h1-6,8,11,16,18H,7,9-10,12-13H2/t16-,18+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 7',8'-Dihydroobolactone

The leaves of Cryptocarya obovata.

Biological Activity of 7',8'-Dihydroobolactone

Description1. 7',8'-Dihydroobolactone can inhibit Trypanosoma brucei brucei with an IC(50) of 2.8 microM.
TargetsAntifection

7',8'-Dihydroobolactone Dilution Calculator

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7',8'-Dihydroobolactone Molarity Calculator

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Preparing Stock Solutions of 7',8'-Dihydroobolactone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2014 mL 16.0072 mL 32.0143 mL 64.0287 mL 80.0359 mL
5 mM 0.6403 mL 3.2014 mL 6.4029 mL 12.8057 mL 16.0072 mL
10 mM 0.3201 mL 1.6007 mL 3.2014 mL 6.4029 mL 8.0036 mL
50 mM 0.064 mL 0.3201 mL 0.6403 mL 1.2806 mL 1.6007 mL
100 mM 0.032 mL 0.1601 mL 0.3201 mL 0.6403 mL 0.8004 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 7',8'-Dihydroobolactone

7',8'-Dihydroobolactone, a typanocidal alpha-pyrone from the rainforest tree Cryptocarya obovata.[Pubmed:20558060]

Bioorg Med Chem Lett. 2010 Jul 15;20(14):4057-9.

Mass-directed isolation of the CH(2)Cl(2)/MeOH extract from the leaves of Cryptocarya obovata resulted in the purification of a new trypanocidal alpha-pyrone, 7',8'-dihydroobolactone (1). The chemical structure of 1 was determined by 1D/2D NMR, MS and CD data analysis. 7',8'-Dihydroobolactone was shown to inhibit Trypanosoma brucei brucei with an IC(50) of 2.8 microM.

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