Bernardioside A

CAS# 121368-52-3

Bernardioside A

Catalog No. BCN7862----Order now to get a substantial discount!

Product Name & Size Price Stock
Bernardioside A: 5mg $385 In Stock
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Quality Control of Bernardioside A

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Chemical structure

Bernardioside A

3D structure

Chemical Properties of Bernardioside A

Cas No. 121368-52-3 SDF Download SDF
PubChem ID 14699964 Appearance Powder
Formula C36H58O11 M.Wt 666.84
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4aR,5R,6aR,6aS,6bR,8aR,9R,10R,11S,12aR,14bS)-5,11-dihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
SMILES CC1(CCC2(C(C1)C3=CCC4C(C3(CC2O)C)(CCC5C4(CC(C(C5(C)CO)OC6C(C(C(C(O6)CO)O)O)O)O)C)C)C(=O)O)C
Standard InChIKey XFVGJHHHDVZQFB-FWVVSBQTSA-N
Standard InChI InChI=1S/C36H58O11/c1-31(2)11-12-36(30(44)45)19(13-31)18-7-8-23-32(3)14-20(39)28(47-29-27(43)26(42)25(41)21(16-37)46-29)33(4,17-38)22(32)9-10-34(23,5)35(18,6)15-24(36)40/h7,19-29,37-43H,8-17H2,1-6H3,(H,44,45)/t19-,20-,21+,22+,23+,24+,25+,26-,27+,28-,29-,32-,33-,34+,35+,36+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Bernardioside A

The flowers of Bellis perennis.

Biological Activity of Bernardioside A

In vitro

Perennisosides I−VII, Acylated Triterpene Saponins with Antihyperlipidemic Activities from the Flowers of Bellis perennis[Reference: WebLink]

Journal of Natural Products, 2008, 71(5):828-835.


METHODS AND RESULTS:
The methanolic extract and its saponin fraction (methanol-eluted fraction) of the flowers of Bellis perennis were found to suppress serum triglyceride elevation in olive oil-treated mice. From the saponin fraction, seven new triterpene saponins, perennisosides I (1), II (2), III (3), IV (4), V (5), VI (6), and VII (7), were isolated together with four known saponins, bellidioside A (8), asterbatanoside D (9), bernardioside B 2 (10), and bellissaponin BS6 (11). The stereostructures of 1- 7 were elucidated on the basis of chemical and spectroscopic evidence.
CONCLUSIONS:
Among these saponins, perennisosides I (1) and II (2) showed inhibitory effects on serum triglyceride elevation at doses of 25-50 mg/kg, po.

Bernardioside A Dilution Calculator

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Bernardioside A Molarity Calculator

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Preparing Stock Solutions of Bernardioside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4996 mL 7.4981 mL 14.9961 mL 29.9922 mL 37.4903 mL
5 mM 0.2999 mL 1.4996 mL 2.9992 mL 5.9984 mL 7.4981 mL
10 mM 0.15 mL 0.7498 mL 1.4996 mL 2.9992 mL 3.749 mL
50 mM 0.03 mL 0.15 mL 0.2999 mL 0.5998 mL 0.7498 mL
100 mM 0.015 mL 0.075 mL 0.15 mL 0.2999 mL 0.3749 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

Bernardioside A is a triterpenoid saponin isolated from Bellis bernardii.

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