Boeravinone B

CAS# 114567-34-9

Boeravinone B

Catalog No. BCN6466----Order now to get a substantial discount!

Product Name & Size Price Stock
Boeravinone B: 5mg $799 In Stock
Boeravinone B: 10mg Please Inquire In Stock
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Quality Control of Boeravinone B

Number of papers citing our products

Chemical structure

Boeravinone B

3D structure

Chemical Properties of Boeravinone B

Cas No. 114567-34-9 SDF Download SDF
PubChem ID 14018348 Appearance Yellow powder
Formula C17H12O6 M.Wt 312.3
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in acetone and methanol; insoluble in water
Chemical Name 6,9,11-trihydroxy-10-methyl-6H-chromeno[3,4-b]chromen-12-one
SMILES CC1=C(C=C2C(=C1O)C(=O)C3=C(O2)C(OC4=CC=CC=C43)O)O
Standard InChIKey YVVDYYFGAWQOGB-UHFFFAOYSA-N
Standard InChI InChI=1S/C17H12O6/c1-7-9(18)6-11-13(14(7)19)15(20)12-8-4-2-3-5-10(8)23-17(21)16(12)22-11/h2-6,17-19,21H,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Boeravinone B

The roots of Boerhaavia coccinea

Biological Activity of Boeravinone B

Description1. Boeravinone B exhibits significant anti-inflammatory activity (56.6% at 50 mg/kg) when evaluated in an in vivo carrageenan-induced rat paw model. 2. Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for further development.
TargetsAntifection | COX

Boeravinone B Dilution Calculator

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Boeravinone B Molarity Calculator

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Preparing Stock Solutions of Boeravinone B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.202 mL 16.0102 mL 32.0205 mL 64.041 mL 80.0512 mL
5 mM 0.6404 mL 3.202 mL 6.4041 mL 12.8082 mL 16.0102 mL
10 mM 0.3202 mL 1.601 mL 3.202 mL 6.4041 mL 8.0051 mL
50 mM 0.064 mL 0.3202 mL 0.6404 mL 1.2808 mL 1.601 mL
100 mM 0.032 mL 0.1601 mL 0.3202 mL 0.6404 mL 0.8005 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Boeravinone B

Rotenoids from Boerhaavia diffusa as potential anti-inflammatory agents.[Pubmed:23914900]

J Nat Prod. 2013 Aug 23;76(8):1393-8.

Five new (2, 3, 5, 7, and 9) and four known rotenoids (1, 4, 6, and 8) were isolated from a methanol extract of Boerhaavia diffusa roots. The structures of the new rotenoids were elucidated by spectroscopic data interpretation. The 70% ethanol extract, a rotenoid-rich fraction, and all isolated rotenoids were evaluated for their COX-1 and COX-2 inhibitory activities. Among the rotenoids tested, compound 7 showed the most potent COX-1 and COX-2 inhibition, with IC(5)(0) values of 21.7 +/- 0.5 and 25.5 +/- 0.6 muM, respectively. Boeravinone B (6) exhibited significant anti-inflammatory activity (56.6% at 50 mg/kg) when evaluated in an in vivo carrageenan-induced rat paw model.

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