Curcumadionol

CAS# 1235984-45-8

Curcumadionol

Catalog No. BCN3561----Order now to get a substantial discount!

Product Name & Size Price Stock
Curcumadionol: 5mg Please Inquire In Stock
Curcumadionol: 10mg Please Inquire In Stock
Curcumadionol: 20mg Please Inquire Please Inquire
Curcumadionol: 50mg Please Inquire Please Inquire
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Curcumadionol: 500mg Please Inquire Please Inquire
Curcumadionol: 1000mg Please Inquire Please Inquire

Quality Control of Curcumadionol

Number of papers citing our products

Chemical structure

Curcumadionol

3D structure

Chemical Properties of Curcumadionol

Cas No. 1235984-45-8 SDF Download SDF
PubChem ID 73356517 Appearance Cryst.
Formula C15H20O3 M.Wt 248.3
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-(2-hydroxypropan-2-yl)-6-methyl-5-(3-oxobutyl)cyclohepta-2,4,6-trien-1-one
SMILES CC1=CC(=O)C(=CC=C1CCC(=O)C)C(C)(C)O
Standard InChIKey ZJOGLHNZNCCGQF-UHFFFAOYSA-N
Standard InChI InChI=1S/C15H20O3/c1-10-9-14(17)13(15(3,4)18)8-7-12(10)6-5-11(2)16/h7-9,18H,5-6H2,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Curcumadionol

The rhizomes of Curcuma rcenyujin

Biological Activity of Curcumadionol

DescriptionStandard reference

Protocol of Curcumadionol

Structure Identification
Chem Biodivers. 2010 May;7(5):1245-53.

Four new sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric-oxide production.[Pubmed: 20491080]


METHODS AND RESULTS:
Four new sesquiterpenes including the novel sesquiterpene lactone (6R)-dehydroxysipanolinolide (1), two new eudesmane-type sesquiterpenes, curcolide (2) and curcodione (3), and a new xanthane-type sesquiterpene, Curcumadionol (4), were isolated from Curcuma wenyujin Y. H. Chen et C. Ling, together with five known ones, 5-9. The structures of the new compounds were elucidated by spectroscopic methods. The inhibitory effects of compounds 1-9 on nitric-oxide production in lipopolysaccaride-activated macrophages were evaluated.

Curcumadionol Dilution Calculator

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Curcumadionol Molarity Calculator

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Preparing Stock Solutions of Curcumadionol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0274 mL 20.1369 mL 40.2739 mL 80.5477 mL 100.6847 mL
5 mM 0.8055 mL 4.0274 mL 8.0548 mL 16.1095 mL 20.1369 mL
10 mM 0.4027 mL 2.0137 mL 4.0274 mL 8.0548 mL 10.0685 mL
50 mM 0.0805 mL 0.4027 mL 0.8055 mL 1.611 mL 2.0137 mL
100 mM 0.0403 mL 0.2014 mL 0.4027 mL 0.8055 mL 1.0068 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Curcumadionol

Four new sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric-oxide production.[Pubmed:20491080]

Chem Biodivers. 2010 May;7(5):1245-53.

Four new sesquiterpenes including the novel sesquiterpene lactone (6R)-dehydroxysipanolinolide (1), two new eudesmane-type sesquiterpenes, curcolide (2) and curcodione (3), and a new xanthane-type sesquiterpene, Curcumadionol (4), were isolated from Curcuma wenyujin Y. H. Chen et C. Ling, together with five known ones, 5-9. The structures of the new compounds were elucidated by spectroscopic methods. The inhibitory effects of compounds 1-9 on nitric-oxide production in lipopolysaccaride-activated macrophages were evaluated.

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