Ganoderic acid K

CAS# 104700-95-0

Ganoderic acid K

Catalog No. BCN3039----Order now to get a substantial discount!

Product Name & Size Price Stock
Ganoderic acid K: 5mg Please Inquire In Stock
Ganoderic acid K: 10mg Please Inquire In Stock
Ganoderic acid K: 20mg Please Inquire Please Inquire
Ganoderic acid K: 50mg Please Inquire Please Inquire
Ganoderic acid K: 100mg Please Inquire Please Inquire
Ganoderic acid K: 200mg Please Inquire Please Inquire
Ganoderic acid K: 500mg Please Inquire Please Inquire
Ganoderic acid K: 1000mg Please Inquire Please Inquire

Quality Control of Ganoderic acid K

Number of papers citing our products

Chemical structure

Ganoderic acid K

3D structure

Chemical Properties of Ganoderic acid K

Cas No. 104700-95-0 SDF Download SDF
PubChem ID 74036828 Appearance Powder
Formula C32H46O9 M.Wt 574.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6-(12-acetyloxy-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid
SMILES CC(CC(=O)CC(C)C(=O)O)C1CC(=O)C2(C1(C(C(=O)C3=C2C(CC4C3(CCC(C4(C)C)O)C)O)OC(=O)C)C)C
Standard InChIKey OEHYQHPDUCRLMW-UHFFFAOYSA-N
Standard InChI InChI=1S/C32H46O9/c1-15(11-18(34)12-16(2)28(39)40)19-13-23(37)32(8)24-20(35)14-21-29(4,5)22(36)9-10-30(21,6)25(24)26(38)27(31(19,32)7)41-17(3)33/h15-16,19-22,27,35-36H,9-14H2,1-8H3,(H,39,40)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ganoderic acid K

The fruit body of Ganoderma lucidum

Biological Activity of Ganoderic acid K

Description1. Ganoderic acid K has anti-tumor activity. 2. Ganoderic acid K has anti-inflammatory activity. 3. Ganoderic acid K is an angiotensin-converting enzyme inhibitor.
TargetsImmunology & Inflammation related

Ganoderic acid K Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Ganoderic acid K Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Ganoderic acid K

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.74 mL 8.7002 mL 17.4004 mL 34.8008 mL 43.501 mL
5 mM 0.348 mL 1.74 mL 3.4801 mL 6.9602 mL 8.7002 mL
10 mM 0.174 mL 0.87 mL 1.74 mL 3.4801 mL 4.3501 mL
50 mM 0.0348 mL 0.174 mL 0.348 mL 0.696 mL 0.87 mL
100 mM 0.0174 mL 0.087 mL 0.174 mL 0.348 mL 0.435 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Ganoderic acid K

Effects of triterpenes from Ganoderma lucidum on protein expression profile of HeLa cells.[Pubmed:20092987]

Phytomedicine. 2010 Jul;17(8-9):606-13.

To elucidate the cytotoxicity mechanism of Ganoderma triterpenes, a chemoproteomic study using five purified ganoderic acids, ganoderic acid F (GAF), Ganoderic acid K (GAK), ganoderic B (GAB), ganoderic acid D (GAD) and ganoderic acid AM1 (GAAM1) was conducted. GAF, GAK, GAB, GAD and GAAM1 treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with IC(50) values of 19.5+/-0.6 microM, 15.1+/-0.5 microM, 20.3+/-0.4 microM, 17.3+/-0.3 microM, 19.8+/-0.7 microM, respectively. The protein expression profiles of HeLa cells treated with each ganoderic acid at dose of 15 microM for 48 h were checked using two-dimensional electrophoresis (2-DE). The possible target-related proteins of ganoderic acids, i.e. proteins with same change tendency in all five ganoderic acids-treated groups compared with control, were identified using MALDI-TOF MS/MS. Twelve proteins including human interleukin-17E, eukaryotic translation initiation factor 5A (eIF5A), peroxiredoxin 2, ubiquilin 2, Cu/Zn-superoxide dismutase, 14-3-3 beta/alpha, TPM4-ALK fusion oncoprotein type 2, PP2A subunit A PR65-alpha isoform, nucleobindin-1, heterogeneous nuclear ribonucleoprotein K, reticulocalbin 1 and chain A of DJ-1 protein were identified. Ganoderic acids might exert their cytotoxicity by altering proteins involved in cell proliferation and/or cell death, carcinogenosis, oxidative stress, calcium signaling and ER stress.

Keywords:

Ganoderic acid K,104700-95-0,Natural Products, buy Ganoderic acid K , Ganoderic acid K supplier , purchase Ganoderic acid K , Ganoderic acid K cost , Ganoderic acid K manufacturer , order Ganoderic acid K , high purity Ganoderic acid K

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: