HOSu

CAS# 6066-82-6

HOSu

Catalog No. BCC2845----Order now to get a substantial discount!

Product Name & Size Price Stock
HOSu: 5mg $6 In Stock
HOSu: 10mg Please Inquire In Stock
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Quality Control of HOSu

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Chemical structure

HOSu

3D structure

Chemical Properties of HOSu

Cas No. 6066-82-6 SDF Download SDF
PubChem ID 80170 Appearance Powder
Formula C4H5NO3 M.Wt 115.1
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-hydroxypyrrolidine-2,5-dione
SMILES C1CC(=O)N(C1=O)O
Standard InChIKey NQTADLQHYWFPDB-UHFFFAOYSA-N
Standard InChI InChI=1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

HOSu Dilution Calculator

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HOSu Molarity Calculator

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Preparing Stock Solutions of HOSu

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 8.6881 mL 43.4405 mL 86.881 mL 173.7619 mL 217.2024 mL
5 mM 1.7376 mL 8.6881 mL 17.3762 mL 34.7524 mL 43.4405 mL
10 mM 0.8688 mL 4.344 mL 8.6881 mL 17.3762 mL 21.7202 mL
50 mM 0.1738 mL 0.8688 mL 1.7376 mL 3.4752 mL 4.344 mL
100 mM 0.0869 mL 0.4344 mL 0.8688 mL 1.7376 mL 2.172 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on HOSu

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References on HOSu

Reactions of monoaryl-substituted methylenecyclobutanes and methylenecyclopropanes with 1-hydroxybenzotriazole (HOBt), 1-hydroxy-7-azabenzotriazole (HOAt), and 1-hydroxysuccinimide (HOSu).[Pubmed:19222218]

J Org Chem. 2009 Mar 20;74(6):2516-20.

Monoaryl-substituted methylenecyclobutanes (MCBs) and methylenecyclopropanes (MCPs) react with 1-hydroxybenzotriazole (HOBt), 1-hydroxy-7-azabenzotriazole (HOAt), and 1-hydroxysuccinimide (HOSu) smoothly to produce the corresponding cyclobutylmethanone and cyclopropylmethanone derivatives 2, 4, and 5 via a cascade epoxidation and nucleophilic addition process or the corresponding epoxides 6 in moderate to good yields under mild conditions. A plausible mechanism has been proposed on the basis of the control experiments and the isolation of the reaction intermediates.

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