Heudelotinone

CAS# 133453-58-4

Heudelotinone

Catalog No. BCN6180----Order now to get a substantial discount!

Product Name & Size Price Stock
Heudelotinone: 5mg $886 In Stock
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Quality Control of Heudelotinone

Number of papers citing our products

Chemical structure

Heudelotinone

3D structure

Chemical Properties of Heudelotinone

Cas No. 133453-58-4 SDF Download SDF
PubChem ID 14779669 Appearance Yellow powder
Formula C18H20O2 M.Wt 268.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4aR)-9-hydroxy-4,4,8-trimethyl-5,6-dihydro-4aH-dibenzo[4,3-[7]annulen-3-one
SMILES CC1=C(C=C2C=C3C=CC(=O)C(C3CCC2=C1)(C)C)O
Standard InChIKey CGDLYSDMNSOBAM-OAHLLOKOSA-N
Standard InChI InChI=1S/C18H20O2/c1-11-8-12-4-6-15-13(9-14(12)10-16(11)19)5-7-17(20)18(15,2)3/h5,7-10,15,19H,4,6H2,1-3H3/t15-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Heudelotinone

The branchs of Jatropha carcas L.

Biological Activity of Heudelotinone

Description1. Heudelotinone shows cytotoxicity against three cancer cell lines A549, Hela, and SMMC-7721( IC50 values of 16.04, 10.67 and 21.68 uM , respectively).

Heudelotinone Dilution Calculator

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Heudelotinone Molarity Calculator

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Preparing Stock Solutions of Heudelotinone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7258 mL 18.6289 mL 37.2578 mL 74.5156 mL 93.1446 mL
5 mM 0.7452 mL 3.7258 mL 7.4516 mL 14.9031 mL 18.6289 mL
10 mM 0.3726 mL 1.8629 mL 3.7258 mL 7.4516 mL 9.3145 mL
50 mM 0.0745 mL 0.3726 mL 0.7452 mL 1.4903 mL 1.8629 mL
100 mM 0.0373 mL 0.1863 mL 0.3726 mL 0.7452 mL 0.9314 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Heudelotinone

New lathyrane and podocarpane diterpenoids from Jatropha curcas.[Pubmed:15133216]

Chem Pharm Bull (Tokyo). 2004 May;52(5):608-11.

Chemical investigation on Jatropha curcas resulted in the isolation of twenty constituents among which four diterpenoids were unknown and six compounds, tetradecyl-(E)-ferulate, 3-O-(Z)-coumaroyl oleanolic acid, Heudelotinone, epi-isojatrogrossidione, 2alpha-hydroxy-epi-isojatrogrossidione, and 2-methyanthraquinone had not been reported earlier from this species. The structures of the new compounds were established by extensive studies of their 1D- and 2D-NMR spectra.

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