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Laurycolactone B

CAS# 85643-77-2

Laurycolactone B

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Quality Control of Laurycolactone B

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Chemical structure

Laurycolactone B

3D structure

Chemical Properties of Laurycolactone B

Cas No. 85643-77-2 SDF Download SDF
PubChem ID 46878903 Appearance Cryst.
Formula C18H20O5 M.Wt 316.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1C2C(C3C(C1C(=O)O2)(C(=O)C=C4C3(C(=O)C=C4C)C)C)O
Standard InChIKey CHTGFNQFMFSMRT-SGRYNZJISA-N
Standard InChI InChI=1S/C18H20O5/c1-7-5-10(19)17(3)9(7)6-11(20)18(4)12-8(2)14(23-16(12)22)13(21)15(17)18/h5-6,8,12-15,21H,1-4H3/t8-,12-,13+,14-,15-,17-,18+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Laurycolactone B

DescriptionLaurycolactone B is a natural product from Eurycoma longifolia Jack.

Protocol of Laurycolactone B

Structure Identification
Tetrahedron Letters, 1982 , 23 (49) :5159-5162.

Structure of laurycolactone A and B, new C18 - quassinoids from Eurycoma longifolia and revised structured of Eurycomalactone (X - ray analysis)[Reference: WebLink]


METHODS AND RESULTS:
Laurycolactone A and Laurycolactone B are new quassinoids with a C18 basic skeleton isolated from the Vietnamese Simaroubaceae, Eurycoma longifolia Jack. The structure of Eurycomalactone, a C19 quassinoid isolated previously from the same plant, has been revised and shown to be .
CONCLUSIONS:
The structures have been established by spectral means and those of and confirmed by X-ray diffraction analysis.

Phytochemistry. 2002 Apr;59(8):833-7.

Quassinoids from Eurycoma longifolia.[Pubmed: 11937162]


METHODS AND RESULTS:
Three quassinoids, eurycolactone D (1), eurycolactone E (2) and eurycolactone F (3) were isolated from the roots of Eurycoma longifolia Jack.
CONCLUSIONS:
The structures of 1-3 were elucidated by spectroscopic methods, and that of 3 was further confirmed by X-ray crystallography. The known quassinoids, Laurycolactone B (4) and eurycomalactone (5) were also identified.

Laurycolactone B Dilution Calculator

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Laurycolactone B Molarity Calculator

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Preparing Stock Solutions of Laurycolactone B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1606 mL 15.8028 mL 31.6056 mL 63.2111 mL 79.0139 mL
5 mM 0.6321 mL 3.1606 mL 6.3211 mL 12.6422 mL 15.8028 mL
10 mM 0.3161 mL 1.5803 mL 3.1606 mL 6.3211 mL 7.9014 mL
50 mM 0.0632 mL 0.3161 mL 0.6321 mL 1.2642 mL 1.5803 mL
100 mM 0.0316 mL 0.158 mL 0.3161 mL 0.6321 mL 0.7901 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Laurycolactone B

Quassinoids from Eurycoma longifolia.[Pubmed:11937162]

Phytochemistry. 2002 Apr;59(8):833-7.

Three quassinoids, eurycolactone D (1), eurycolactone E (2) and eurycolactone F (3) were isolated from the roots of Eurycoma longifolia Jack. The structures of 1-3 were elucidated by spectroscopic methods, and that of 3 was further confirmed by X-ray crystallography. The known quassinoids, Laurycolactone B (4) and eurycomalactone (5) were also identified.

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