Home >> Research Area >>Natural Products>>Alkaloids>> Preskimmianine

Preskimmianine

CAS# 38695-41-9

Preskimmianine

Catalog No. BCN6667----Order now to get a substantial discount!

Product Name & Size Price Stock
Preskimmianine: 5mg $725 In Stock
Preskimmianine: 10mg Please Inquire In Stock
Preskimmianine: 20mg Please Inquire Please Inquire
Preskimmianine: 50mg Please Inquire Please Inquire
Preskimmianine: 100mg Please Inquire Please Inquire
Preskimmianine: 200mg Please Inquire Please Inquire
Preskimmianine: 500mg Please Inquire Please Inquire
Preskimmianine: 1000mg Please Inquire Please Inquire

Quality Control of Preskimmianine

Number of papers citing our products

Chemical structure

Preskimmianine

3D structure

Chemical Properties of Preskimmianine

Cas No. 38695-41-9 SDF Download SDF
PubChem ID 12305721 Appearance Powder
Formula C17H21NO4 M.Wt 303.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4,7,8-trimethoxy-3-(3-methylbut-2-enyl)-1H-quinolin-2-one
SMILES CC(=CCC1=C(C2=C(C(=C(C=C2)OC)OC)NC1=O)OC)C
Standard InChIKey OAEZQCLAAGSHHA-UHFFFAOYSA-N
Standard InChI InChI=1S/C17H21NO4/c1-10(2)6-7-12-15(21-4)11-8-9-13(20-3)16(22-5)14(11)18-17(12)19/h6,8-9H,7H2,1-5H3,(H,18,19)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Preskimmianine

The root barks of Dictamnus dasycarpus.

Biological Activity of Preskimmianine

Description1. Preskimmianine is the biogenetic precursor of skimmianine. 2. Preskimmianine can significantly inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells.
TargetsNO

Preskimmianine Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Preskimmianine Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Preskimmianine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.296 mL 16.4799 mL 32.9598 mL 65.9196 mL 82.3995 mL
5 mM 0.6592 mL 3.296 mL 6.592 mL 13.1839 mL 16.4799 mL
10 mM 0.3296 mL 1.648 mL 3.296 mL 6.592 mL 8.2399 mL
50 mM 0.0659 mL 0.3296 mL 0.6592 mL 1.3184 mL 1.648 mL
100 mM 0.033 mL 0.1648 mL 0.3296 mL 0.6592 mL 0.824 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Preskimmianine

Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells.[Pubmed:21827366]

J Enzyme Inhib Med Chem. 2012 Aug;27(4):490-4.

The methanolic extract of Dictamnus dasycarpus root barks afforded one new glycosidic quinoline alkaloid, 3-[1beta-hydroxy-2-(beta-D-glucopyranosyloxy)-ethyl)-4-methoxy-2(1H)-quinolinone (1), together with nine known compounds, Preskimmianine (2), 8-methoxy-N-methylflindersine (3), dictamine (4), gamma-fagarine (5), halopine (6), skimmianine (7), dictangustine-A (8), iso-gamma-fagarine (9), isomaculosidine (10). The isolated alkaloids significantly inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells. Among them, compounds 3 and 7 showed the most potent inhibitory activities on LPS-induced NO production.

Keywords:

Preskimmianine,38695-41-9,Natural Products, buy Preskimmianine , Preskimmianine supplier , purchase Preskimmianine , Preskimmianine cost , Preskimmianine manufacturer , order Preskimmianine , high purity Preskimmianine

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: