Rubiprasin B

CAS# 125263-66-3

Rubiprasin B

Catalog No. BCN7137----Order now to get a substantial discount!

Product Name & Size Price Stock
Rubiprasin B: 5mg $914 In Stock
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Quality Control of Rubiprasin B

Number of papers citing our products

Chemical structure

Rubiprasin B

3D structure

Chemical Properties of Rubiprasin B

Cas No. 125263-66-3 SDF Download SDF
PubChem ID 21594133 Appearance Powder
Formula C32H52O4 M.Wt 500.76
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(3S,4aR,6aR,6aS,6bS,8aR,12aR,14aR,14bR)-6a-hydroxy-4,4,6a,6b,8a,11,11,14b-octamethyl-13-oxo-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate
SMILES CC(=O)OC1CCC2(C(C1(C)C)CCC3(C2CC(=O)C4(C3(CCC5(C4CC(CC5)(C)C)C)C)O)C)C
Standard InChIKey GWMSDMQWKMSCJR-WWPUQACTSA-N
Standard InChI InChI=1S/C32H52O4/c1-20(33)36-25-11-12-29(7)21(27(25,4)5)10-13-30(8)22(29)18-24(34)32(35)23-19-26(2,3)14-15-28(23,6)16-17-31(30,32)9/h21-23,25,35H,10-19H2,1-9H3/t21-,22+,23+,25-,28+,29-,30+,31-,32+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rubiprasin B

The roots of Rubia cordifolia var. pratensis.

Biological Activity of Rubiprasin B

DescriptionRubiprasin B is a natural product from Rubia cordifolia var. pratensis.

Protocol of Rubiprasin B

Structure Identification
Chem. Pharm. Bull.,1989,37(6):1670-1672.

New triterpenoids from Rubia cordifolia var. pratensis (Rubiaceae)[Reference: WebLink]

From the roots of Rubia cordifolia var. pratensis, three new triterpenoids named rubiprasin A, Rubiprasin B and rubiprasin C have been isolated and their structures were determined as 3β-acetoxyoleanane-13β, 15α-diol-12-one, 3β-acetoxyoleanace-13β-ol-12-one and 3β-acetoxyl-19α-hydroxyolean-12-en-28-oic acid respectively by various chemical and spectroscopic methods including 1H-1H COSY, 1H-13C COSY and X-ray diffractions.

Rubiprasin B Dilution Calculator

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Rubiprasin B Molarity Calculator

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Preparing Stock Solutions of Rubiprasin B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.997 mL 9.9848 mL 19.9696 mL 39.9393 mL 49.9241 mL
5 mM 0.3994 mL 1.997 mL 3.9939 mL 7.9879 mL 9.9848 mL
10 mM 0.1997 mL 0.9985 mL 1.997 mL 3.9939 mL 4.9924 mL
50 mM 0.0399 mL 0.1997 mL 0.3994 mL 0.7988 mL 0.9985 mL
100 mM 0.02 mL 0.0998 mL 0.1997 mL 0.3994 mL 0.4992 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rubiprasin B

[Chemical constituents from roots and rhizomes of Rubia oncotricha and their cytotoxic activities].[Pubmed:30593239]

Zhongguo Zhong Yao Za Zhi. 2018 Nov;43(22):4462-4468.

Fourteen compounds, including rubiprasin D (1), Rubiprasin B (2), rubiprasin C (3), oleanolic acid (4), methyl-5-hydroxy-dinaphtho[1, 2-2'3']furan-7, 12-dione-6-carboxylate (5), rubioncolin C (6), mollugin (7), furomollugin (8), 3-amino-2-methoxycarbonyl-1, 4-naphthoquinone (9), 1-hydroxy-2-methyl-9, 10-anthraquinone (10), 2-hydroxy-6-methyl-9, 10-anthraquinone (11), 1, 4-dihydroxy-2-hydroxymethyl-9, 10-anthraquinone (12), 2-hydroxy-1-methoxy-9, 10-anthraquinone (13), and 1-hydroxy-2-methoxy-6-methyl-9, 10-anthraquinone(14), were isolated from the methanol extract of the roots and rhizomes of Rubia oncotricha using various column chromatographies. Their structures were mainly determined on basis of NMR and MS spectroscopic data analyses. Among them, 1 is a new oleanane triterpene, and compounds 2-5, 9 and 11-13 were obtained from this plant for the first time. Cytotoxic and nematicidal activities of all these compounds were evaluated, and the results showed that only 4, 6, 11 and 12 exhibited cytotoxicities against A549, SGC-7901 and HeLa cancer cell lines. The IC(5)(0) of 6 were 19.42, 2.74, 8.07 mumol.L(-)(1), respectively.

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