Taxcultine

CAS# 153415-46-4

Taxcultine

Catalog No. BCN6948----Order now to get a substantial discount!

Product Name & Size Price Stock
Taxcultine: 5mg $914 In Stock
Taxcultine: 10mg Please Inquire In Stock
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Quality Control of Taxcultine

Number of papers citing our products

Chemical structure

Taxcultine

3D structure

Chemical Properties of Taxcultine

Cas No. 153415-46-4 SDF Download SDF
PubChem ID 3081898 Appearance Powder
Formula C44H53NO14 M.Wt 819.90
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CCCC(=O)NC(C1=CC=CC=C1)C(C(=O)OC2CC3(C(C4C(C(CC5C4(CO5)OC(=O)C)O)(C(=O)C(C(=C2C)C3(C)C)OC(=O)C)C)OC(=O)C6=CC=CC=C6)O)O
Standard InChIKey SXPIMOCRRJUHJY-MNLIZOKASA-N
Standard InChI InChI=1S/C44H53NO14/c1-8-15-31(49)45-33(26-16-11-9-12-17-26)34(50)40(53)57-28-21-44(54)38(58-39(52)27-18-13-10-14-19-27)36-42(7,29(48)20-30-43(36,22-55-30)59-25(4)47)37(51)35(56-24(3)46)32(23(28)2)41(44,5)6/h9-14,16-19,28-30,33-36,38,48,50,54H,8,15,20-22H2,1-7H3,(H,45,49)/t28-,29-,30+,33-,34+,35+,36-,38-,42+,43-,44+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Taxcultine

The cell cultures of Taxus baccata.

Biological Activity of Taxcultine

Description1. Taxcultine can actively promote tubulin assembly.

Taxcultine Dilution Calculator

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Taxcultine Molarity Calculator

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Preparing Stock Solutions of Taxcultine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.2197 mL 6.0983 mL 12.1966 mL 24.3932 mL 30.4915 mL
5 mM 0.2439 mL 1.2197 mL 2.4393 mL 4.8786 mL 6.0983 mL
10 mM 0.122 mL 0.6098 mL 1.2197 mL 2.4393 mL 3.0492 mL
50 mM 0.0244 mL 0.122 mL 0.2439 mL 0.4879 mL 0.6098 mL
100 mM 0.0122 mL 0.061 mL 0.122 mL 0.2439 mL 0.3049 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Taxcultine

Isolation and semi-synthesis of a bioactive taxane from Taxus canadensis.[Pubmed:8835457]

Phytochemistry. 1996 Feb;41(3):803-5.

A minor bioactive taxane, isolated from the needles of Taxus canadensis and semi-synthesized, was shown to be Taxcultine.

New bioactive taxoids from cell cultures of Taxus baccata.[Pubmed:7908950]

J Nat Prod. 1994 Jan;57(1):116-22.

Four new taxoids were isolated from cell cultures of Taxus baccata. Their structures were elucidated by spectroscopic analyses. Two were the aglycones corresponding to previously isolated 7-O-xylosides of taxol C [1] and 10-deacetyltaxol C [2]. The third [3] had an N-methylated side-chain, while the fourth, named Taxcultine [4], contained an n-propyl group on the side-chain. All four compounds actively promoted tubulin assembly. Taxol C [1] showed potent and selective cytotoxicity in the NCI human cell line screen.

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