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Trityl candesartan

CAS# 139481-72-4

Trityl candesartan

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Product Name & Size Price Stock
Trityl candesartan: 5mg $17 In Stock
Trityl candesartan: 10mg Please Inquire In Stock
Trityl candesartan: 20mg Please Inquire Please Inquire
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Trityl candesartan: 100mg Please Inquire Please Inquire
Trityl candesartan: 200mg Please Inquire Please Inquire
Trityl candesartan: 500mg Please Inquire Please Inquire
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Chemical structure

Trityl candesartan

3D structure

Chemical Properties of Trityl candesartan

Cas No. 139481-72-4 SDF Download SDF
PubChem ID 10312563 Appearance Powder
Formula C43H34N6O3 M.Wt 682.8
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-ethoxy-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
SMILES CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NN=NN5C(C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)C(=O)O
Standard InChIKey VBMKOTRJWPIKMG-UHFFFAOYSA-N
Standard InChI InChI=1S/C43H34N6O3/c1-2-52-42-44-38-24-14-23-37(41(50)51)39(38)48(42)29-30-25-27-31(28-26-30)35-21-12-13-22-36(35)40-45-46-47-49(40)43(32-15-6-3-7-16-32,33-17-8-4-9-18-33)34-19-10-5-11-20-34/h3-28H,2,29H2,1H3,(H,50,51)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Trityl candesartan Dilution Calculator

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Trityl candesartan Molarity Calculator

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Preparing Stock Solutions of Trityl candesartan

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4646 mL 7.3228 mL 14.6456 mL 29.2912 mL 36.6139 mL
5 mM 0.2929 mL 1.4646 mL 2.9291 mL 5.8582 mL 7.3228 mL
10 mM 0.1465 mL 0.7323 mL 1.4646 mL 2.9291 mL 3.6614 mL
50 mM 0.0293 mL 0.1465 mL 0.2929 mL 0.5858 mL 0.7323 mL
100 mM 0.0146 mL 0.0732 mL 0.1465 mL 0.2929 mL 0.3661 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Trityl candesartan

Improvement of the antihypertensive capacity of candesartan and trityl candesartan by their SOD mimetic copper(II) complexes.[Pubmed:23501135]

J Inorg Biochem. 2013 Jun;123:23-33.

Two new complexes [Cu(Cand)(H2O)4] [1] and [Cu2(TCand)4(H2O)2].4H2O [2] (Cand = candesartan; TCand = Trityl candesartan) have been synthesized and thoroughly characterized. The FTIR, Raman, EPR and diffuse reflectance spectra of the solid compounds show a dimeric complex for [2] with carboxylate bridging of the type found in copper(II) acetate. Both elemental analysis and thermal measurements allow the determination of the total stoichiometries of both complexes. The stability measurements show that the compounds are stable in ethanolic solutions at least for 1h, while the preservation of the overall stochiometry for both species in solution has been determined by spectrophotometric titrations. By metal complexation the absence of antioxidant behavior of both sartans has been improved. Complexes [1] and [2] are strong superoxidedismutase mimetic compounds and complex [2] also behaves as a peroxyl radical scavenger. Furthermore, this higher antioxidant activity works in parallel with the improvement of the expansive activity over the angiotensin II-induced contracted human mesangial cells. These new complexes exhibit even higher efficiency as drugs in comparison with the free non-complexed medication with increased antioxidant ability expressing higher capacity to block the angiotensin II contractile effect. This study provides a new insight into the development of copper(II) complexes as potential drugs.

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