Fmoc-D-N- Me-Val-OH

CAS# 103478-58-6

Fmoc-D-N- Me-Val-OH

Catalog No. BCC3359----Order now to get a substantial discount!

Product Name & Size Price Stock
Fmoc-D-N- Me-Val-OH: 5mg $6 In Stock
Fmoc-D-N- Me-Val-OH: 10mg Please Inquire In Stock
Fmoc-D-N- Me-Val-OH: 20mg Please Inquire Please Inquire
Fmoc-D-N- Me-Val-OH: 50mg Please Inquire Please Inquire
Fmoc-D-N- Me-Val-OH: 100mg Please Inquire Please Inquire
Fmoc-D-N- Me-Val-OH: 200mg Please Inquire Please Inquire
Fmoc-D-N- Me-Val-OH: 500mg Please Inquire Please Inquire
Fmoc-D-N- Me-Val-OH: 1000mg Please Inquire Please Inquire
Related Products
  • PF-4708671

    Catalog No.:BCC5031
    CAS No.:1255517-76-0
  • BIX 02565

    Catalog No.:BCC4303
    CAS No.:1311367-27-7
  • BI-D1870

    Catalog No.:BCC5030
    CAS No.:501437-28-1
  • CMK

    Catalog No.:BCC1489
    CAS No.:821794-90-5

Quality Control of Fmoc-D-N- Me-Val-OH

Number of papers citing our products

Chemical structure

Fmoc-D-N- Me-Val-OH

3D structure

Chemical Properties of Fmoc-D-N- Me-Val-OH

Cas No. 103478-58-6 SDF Download SDF
PubChem ID 16213159 Appearance Powder
Formula C21H23NO4 M.Wt 353.4
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-methylbutanoic acid
SMILES CC(C)C(C(=O)O)N(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Standard InChIKey YCXXXPZNQXXRIG-LJQANCHMSA-N
Standard InChI InChI=1S/C21H23NO4/c1-13(2)19(20(23)24)22(3)21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,12H2,1-3H3,(H,23,24)/t19-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Fmoc-D-N- Me-Val-OH Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Fmoc-D-N- Me-Val-OH Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Fmoc-D-N- Me-Val-OH

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8297 mL 14.1483 mL 28.2965 mL 56.5931 mL 70.7414 mL
5 mM 0.5659 mL 2.8297 mL 5.6593 mL 11.3186 mL 14.1483 mL
10 mM 0.283 mL 1.4148 mL 2.8297 mL 5.6593 mL 7.0741 mL
50 mM 0.0566 mL 0.283 mL 0.5659 mL 1.1319 mL 1.4148 mL
100 mM 0.0283 mL 0.1415 mL 0.283 mL 0.5659 mL 0.7074 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University

Background on Fmoc-D-N- Me-Val-OH

Fmoc-D-N- Me-Val-OH

Featured Products
New Products
 

References on Fmoc-D-N- Me-Val-OH

Peptides from chiral C alpha,alpha-disubstituted glycines. Crystallographic characterization of conformation of C alpha-methyl, C alpha-isopropylglycine [(alpha Me)Val] in simple derivatives and model peptides.[Pubmed:1917310]

Int J Pept Protein Res. 1991 Jun;37(6):521-7.

The molecular and crystal structures of one derivative and three model peptides (to the pentapeptide level) of the chiral C alpha,alpha-disubstituted glycine C alpha-methyl, C alpha-isopropylglycine [(alpha Me)Val] have been determined by X-ray diffraction. The derivative is mClAc-L-(alpha Me)Val-OH, and the peptides are Z-L-(alpha Me)Val-(L-Ala)2-OMe monohydrate, Z-Aib-L-(alpha Me)Val-(Aib)2-OtBu, and Ac-(Aib)2-L-(alpha Me)Val-(Aib)2OtBu acetonitrile solvate. The tripeptide adopts a type-I beta-turn conformation stabilized by a 1----4N--H...O = C intramolecular H-bond. The tetra- and pentapeptides are folded in regular right-handed 3(10)-helices. All four L-(alpha Me)Val residues prefer phi, psi angles in the right-handed helical region of the conformational map. The results indicate that: (i) the (alpha Me)Val residue is a strong type-I/III beta-turn and helix former, and (ii) the relationship between (alpha Me)Val chirality and helix screw sense is the same as that of C alpha-monosubstituted protein amino-acids. The implications for the use of the (alpha Me)Val residue in designing conformationally constrained analogues of bioactive peptides are briefly discussed.

Formation of Fmoc-beta-alanine during Fmoc-protections with Fmoc-OSu.[Pubmed:18219706]

J Pept Sci. 2008 Jun;14(6):763-6.

During the Fmoc-protection of H-alpha-Me-Val-OH, an unknown side product was found and isolated. The characterization using various analytical methods led unambiguously to the result that Fmoc-beta-Ala-OH was formed during the reaction. The reagent Fmoc-OSu was proven to be the source of Fmoc-beta-Ala-OH, following a mechanism that involved many deprotonation and elimination steps and a Lossen-type rearrangement as key sequence. The impurity Fmoc-beta-Ala-OH was found in a variety of reactions in which Fmoc-OSu was applied, either in the reaction mixture or as a contamination of the crude product. Purification of the Fmoc-amino acid derivatives from this impurity incurred high costs and significant reductions in yield.

Keywords:

Fmoc-D-N- Me-Val-OH,103478-58-6,Natural Products,N-Methyl Amino Acids, buy Fmoc-D-N- Me-Val-OH , Fmoc-D-N- Me-Val-OH supplier , purchase Fmoc-D-N- Me-Val-OH , Fmoc-D-N- Me-Val-OH cost , Fmoc-D-N- Me-Val-OH manufacturer , order Fmoc-D-N- Me-Val-OH , high purity Fmoc-D-N- Me-Val-OH

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: