Gelomulide N

CAS# 1005212-02-1

Gelomulide N

Catalog No. BCN6641----Order now to get a substantial discount!

Product Name & Size Price Stock
Gelomulide N: 5mg $989 In Stock
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Quality Control of Gelomulide N

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Chemical structure

Gelomulide N

3D structure

Chemical Properties of Gelomulide N

Cas No. 1005212-02-1 SDF Download SDF
PubChem ID 24775138 Appearance Powder
Formula C24H32O7 M.Wt 432.5
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(1S,3R,8R,10S,11R,12S,14S,16R)-12-acetyloxy-5,11,15,15-tetramethyl-6-oxo-2,7-dioxapentacyclo[8.8.0.01,3.04,8.011,16]octadec-4-en-14-yl] acetate
SMILES CC1=C2C(CC3C4(C(CCC35C2O5)C(C(CC4OC(=O)C)OC(=O)C)(C)C)C)OC1=O
Standard InChIKey YOELDOOOBJSHSZ-SRFZOMHBSA-N
Standard InChI InChI=1S/C24H32O7/c1-11-19-14(30-21(11)27)9-16-23(6)15(7-8-24(16)20(19)31-24)22(4,5)17(28-12(2)25)10-18(23)29-13(3)26/h14-18,20H,7-10H2,1-6H3/t14-,15-,16+,17+,18+,20-,23-,24+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Gelomulide N

The leaves of Suregada glomerulata(Bl.) Baill.

Biological Activity of Gelomulide N

In vitro

Cytotoxic ent-abietane diterpenes from Gelonium aequoreum.[Reference: WebLink]

Phytochemistry, 2008, 69(1):276-287.


METHODS AND RESULTS:
Seventeen ent-abietane diterpenes, including gelomulide K, gelomulide L, gelomulide M, Gelomulide N, gelomulide O, gelomulide P, gelomulide Q, gelomulide R, gelomulide S, gelomulide T, gelomulide U, gelomulide V, gelomulide W, gelomulide X (1–14), and three known compounds, were isolated from a dichloromethane-soluble extract of Gelonium aequoreum through bioassay-guided fractionation. Their structures were identified by spectroscopic methods, and stereochemistry was confirmed by X-ray crystallographic analysis, CD spectral data, and Mosher’s method.
CONCLUSIONS:
The isolates were evaluated for in vitro cytotoxic activity, and compounds 1 and 3 showed moderate cytotoxicity against lung (A549), breast (MDA-MB-231 and MCF7), and liver (HepG2) cancer cell lines.

Gelomulide N Dilution Calculator

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Gelomulide N Molarity Calculator

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Preparing Stock Solutions of Gelomulide N

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3121 mL 11.5607 mL 23.1214 mL 46.2428 mL 57.8035 mL
5 mM 0.4624 mL 2.3121 mL 4.6243 mL 9.2486 mL 11.5607 mL
10 mM 0.2312 mL 1.1561 mL 2.3121 mL 4.6243 mL 5.7803 mL
50 mM 0.0462 mL 0.2312 mL 0.4624 mL 0.9249 mL 1.1561 mL
100 mM 0.0231 mL 0.1156 mL 0.2312 mL 0.4624 mL 0.578 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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