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Koumine N-oxide

CAS# 113900-75-7

Koumine N-oxide

Catalog No. BCN4807----Order now to get a substantial discount!

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Koumine N-oxide: 5mg $1012 In Stock
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Quality Control of Koumine N-oxide

Number of papers citing our products

Chemical structure

Koumine N-oxide

3D structure

Chemical Properties of Koumine N-oxide

Cas No. 113900-75-7 SDF Download SDF
PubChem ID 5318847 Appearance Powder
Formula C20H22N2O2 M.Wt 322.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES C[N+]1(CC2(C3CC4C5=NC6=CC=CC=C6C52CC1C3CO4)C=C)[O-]
Standard InChIKey OISZCFMVBRTVHR-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H22N2O2/c1-3-19-11-22(2,23)16-9-20(19)13-6-4-5-7-15(13)21-18(20)17-8-14(19)12(16)10-24-17/h3-7,12,14,16-17H,1,8-11H2,2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Koumine N-oxide

The herbs of Gelsemium elegans

Biological Activity of Koumine N-oxide

DescriptionKoumine N-oxide is a natural product from Gelsemium elegans.

Protocol of Koumine N-oxide

Structure Identification
Tetrahedron, 1988 , 44 (16) :5075-5094.

Studies on the indole alkaloids of gelsem1um elegans (thailand): structure elucidation and proposal of biogenetic route[Reference: WebLink]


METHODS AND RESULTS:
Chemical investigation of the roots of collected in Thailand resulted in the isolation of the new indole alkaloids, 16-epi-voacarpine, 19-hydroxydihydrogelsevirine, and 19-(Z)-taberpsychine, along with eight known bases.
CONCLUSIONS:
Among them, the structure of “akuammidine” and koumidine were revised to have 19-(Z) ethylidene configuration. From the seeds of 14-hydroxygelsedine was obtained. Furthermore, three new alkaloids, Koumine N-oxide, gelsemine N-oxide, and 19-oxo-gelsenicine, were found from the leaves of . A new and plausible biogenetic route of gelsemium alkaloids is proposed.

Koumine N-oxide Dilution Calculator

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Koumine N-oxide Molarity Calculator

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Preparing Stock Solutions of Koumine N-oxide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1017 mL 15.5087 mL 31.0174 mL 62.0347 mL 77.5434 mL
5 mM 0.6203 mL 3.1017 mL 6.2035 mL 12.4069 mL 15.5087 mL
10 mM 0.3102 mL 1.5509 mL 3.1017 mL 6.2035 mL 7.7543 mL
50 mM 0.062 mL 0.3102 mL 0.6203 mL 1.2407 mL 1.5509 mL
100 mM 0.031 mL 0.1551 mL 0.3102 mL 0.6203 mL 0.7754 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Koumine N-oxide

Studies on the indole alkaloids of gelsem1um elegans (thailand): structure elucidation and proposal of biogenetic route

Tetrahedron, 1988 , 44 (16) :5075-5094.

Chemical investigation of the roots of collected in Thailand resulted in the isolation of the new indole alkaloids, 16-epi-voacarpine, 19-hydroxydihydrogelsevirine, and 19-(Z)-taberpsychine, along with eight known bases. Among them, the structure of “akuammidine” and koumidine were revised to have 19-(Z) ethylidene configuration. From the seeds of 14-hydroxygelsedine was obtained. Furthermore, three new alkaloids, Koumine N-oxide, gelsemine N-oxide, and 19-oxo-gelsenicine, were found from the leaves of . A new and plausible biogenetic route of gelsemium alkaloids is proposed.

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