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Quercetagetin-7-O-glucoside

CAS# 548-75-4

Quercetagetin-7-O-glucoside

Catalog No. BCN6480----Order now to get a substantial discount!

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Quality Control of Quercetagetin-7-O-glucoside

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Chemical structure

Quercetagetin-7-O-glucoside

3D structure

Chemical Properties of Quercetagetin-7-O-glucoside

Cas No. 548-75-4 SDF Download SDF
PubChem ID 5320826 Appearance Yellow powder
Formula C21H20O13 M.Wt 480.4
Type of Compound Flavonoids Storage Desiccate at -20°C
Synonyms 3,3',4',5,6,7-Hexahydroxyflavone 7-glucoside; 6-Hydroxyquercetin 7-glucoside; Quercetagetin 7-glucoside
Solubility DMSO : 250 mg/mL (520.42 mM; Need ultrasonic)
Chemical Name 2-(3,4-dihydroxyphenyl)-3,5,6-trihydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
SMILES C1=CC(=C(C=C1C2=C(C(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O)O)O
Standard InChIKey IDTDRZPBDLMCLB-HSOQPIRZSA-N
Standard InChI InChI=1S/C21H20O13/c22-5-11-14(26)17(29)19(31)21(34-11)33-10-4-9-12(15(27)13(10)25)16(28)18(30)20(32-9)6-1-2-7(23)8(24)3-6/h1-4,11,14,17,19,21-27,29-31H,5H2/t11-,14-,17+,19-,21-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Quercetagetin-7-O-glucoside

1 Calendula sp. 2 Chryasanthemum sp. 3 Coreopsis sp. 4 Eupatorium sp. 5 Helichrysum sp. 6 Inula sp. 7 Rudbeckia sp. 8 Tagetes sp.

Biological Activity of Quercetagetin-7-O-glucoside

Description1. Quercetagetin-7-O-glucoside, quercetagetin, quercetagetin 3'-methyl ether 7-O-glucoside, patuletin, and patuletin 7-O-glucoside are "yellow flavonols", and it was shown that the flower colors of three yellow-flowered species are due to these compounds. 2. Quercetagetin-7-O-glucoside, a potent inhibitor of beta-glucuronidase and lysozyme release, shows anti-inflammatory activity, can significantly inhibit arachidonic acid release from membranes.
TargetsImmunology & Inflammation related

Quercetagetin-7-O-glucoside Dilution Calculator

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Preparing Stock Solutions of Quercetagetin-7-O-glucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0816 mL 10.408 mL 20.816 mL 41.632 mL 52.04 mL
5 mM 0.4163 mL 2.0816 mL 4.1632 mL 8.3264 mL 10.408 mL
10 mM 0.2082 mL 1.0408 mL 2.0816 mL 4.1632 mL 5.204 mL
50 mM 0.0416 mL 0.2082 mL 0.4163 mL 0.8326 mL 1.0408 mL
100 mM 0.0208 mL 0.1041 mL 0.2082 mL 0.4163 mL 0.5204 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Quercetagetin-7-O-glucoside

Influence of anti-inflammatory flavonoids on degranulation and arachidonic acid release in rat neutrophils.[Pubmed:8018254]

Z Naturforsch C. 1994 Mar-Apr;49(3-4):235-40.

We assessed the effects of 24 flavonoid derivatives, reported as anti-inflammatory, on lysosomal enzyme secretion and arachidonic acid release in rat neutrophils. Amentoflavone, Quercetagetin-7-O-glucoside, apigenin, fisetin, kaempferol, luteolin and quercetin were the most potent inhibitors of beta-glucuronidase and lysozyme release. The first compound was also able to inhibit basal release. These flavonoids besides chrysin and to a reduced extent, naringenin, significantly inhibited arachidonic acid release from membranes. A correlation between degranulation and arachidonic acid release was found for this series of compounds. Structure-activity relationships and implications for the anti-inflammatory effects of these flavonoids were discussed.

Anthocyanins and other flavonoids as flower pigments from eleven Centaurea species.[Pubmed:25924526]

Nat Prod Commun. 2015 Mar;10(3):447-50.

Anthocyanins and other flavonoids were isolated from the flowers of eleven Centaurea species, C. macrocephala, C. rupestotilis and C. suaveolens, which produce yellow flowers, and C. achtarovii, C. dealbata, C. montana, C. nigra, C. scabiosa, C. simplicicaulis, C. hypoleuca and C. triumfetti, which have cyanic flowers. Four anthocyanins, cyanidin 3,5-di-O-glucoside, cyanidin 3-O-(6"-malonylglucoside)-5-O-glucoside, cyanidin 3-O-(6"-succinylglucoside)-5- O-glucoside and cyanidin glycoside, were detected in the cyanic flowers of seven Centaurea species. Of these anthocyanins, the first two were found as major anthocyanins. In the cyanic species, four other flavonoids, apigenin 7-O-glucuronide-4'-O-glucoside, malonylated apigenin 7,4'-di-O-glucoside, apigenin 7-0- glucuronide and kaempferol glycoside, were also isolated. On the other hand, nine flavonols and four flavones were isolated from the three yellow-flowered species, and identified as quercetagetin, quercetagetin 7-O-glucoside, quercetagetin 3'-methyl ether 7-O-glucoside, patuletin, patuletin 7-O-glucoside, quercetin 7-O-glucoside, kaempferol 3-methyl ether, kaempferol 3-methyl ether 4'-O-glucuronide and isorhamnetin 3-O-galactoside, and apigenin, apigenin 7- O-glucuronide, luteolin 7-O-glucoside and apigenin 6,8-di-C-glucoside (vicenin-2). Of these flavonoids, the former five flavonols are "yellow flavonols", and it was shown that their flower colors are due to these compounds.

Description

Quercetagitrin (Quercetagetin-7-O-glucoside), isolated from the flowers of the African Marigold (Tagetes erecta), has anti-inflammatory activity.

Keywords:

Quercetagetin-7-O-glucoside,548-75-4,3,3',4',5,6,7-Hexahydroxyflavone 7-glucoside; 6-Hydroxyquercetin 7-glucoside; Quercetagetin 7-glucoside,Natural Products, buy Quercetagetin-7-O-glucoside , Quercetagetin-7-O-glucoside supplier , purchase Quercetagetin-7-O-glucoside , Quercetagetin-7-O-glucoside cost , Quercetagetin-7-O-glucoside manufacturer , order Quercetagetin-7-O-glucoside , high purity Quercetagetin-7-O-glucoside

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