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Binankadsurin A

CAS# 77165-79-8

Binankadsurin A

Catalog No. BCX2021----Order now to get a substantial discount!

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Chemical structure

Binankadsurin A

Chemical Properties of Binankadsurin A

Cas No. 77165-79-8 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C22H26O7 M.Wt 402.48
Type of Compound Lignanoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Binankadsurin A Dilution Calculator

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Binankadsurin A Molarity Calculator

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Preparing Stock Solutions of Binankadsurin A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4846 mL 12.423 mL 24.846 mL 49.6919 mL 62.1149 mL
5 mM 0.4969 mL 2.4846 mL 4.9692 mL 9.9384 mL 12.423 mL
10 mM 0.2485 mL 1.2423 mL 2.4846 mL 4.9692 mL 6.2115 mL
50 mM 0.0497 mL 0.2485 mL 0.4969 mL 0.9938 mL 1.2423 mL
100 mM 0.0248 mL 0.1242 mL 0.2485 mL 0.4969 mL 0.6211 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Binankadsurin A

A new rearranged abietane diterpene and other constituents from Clerodendrum philipinum.[Pubmed:19413107]

Nat Prod Commun. 2009 Mar;4(3):323-5.

From the methanolic extract of the roots of Clerodendrum philipinum, a new rearranged abietane diterpene (1) and eight known compounds were isolated by various chromatography methods. Their structures were identified by means of spectroscopic methods, including 1D- and 2D-NMR, as 17(15-->16),18(4-->3)-bisabeo-11,12,14,16-tetrahydroxy-3,5,8,11,13,15-abietahexaen-7-one (1), Binankadsurin A, clerodenoside A, martynoside, acteoside, isoacteoside, astragalin, p3-sitosterol, and daucosterol. Binankadsurin A was found for the first time from a Clerodendrum species.

Dibenzocyclooctadiene lignans and lanostane derivatives from the roots of Kadsura coccinea and their protective effects on primary rat hepatocyte injury induced by t-butyl hydroperoxide.[Pubmed:19350485]

Planta Med. 2009 Sep;75(11):1253-7.

A new dibenzocyclooctadiene lignan, acetylepigomisin R ( 1), and a new 3,4-seco-lanostane-type triterpene, seco-coccinic acid F ( 2), along with three known dibenzocyclooctadiene lignans, isovaleroylBinankadsurin A ( 3), kadsuralignan J ( 4), and Binankadsurin A ( 5), and one lanostane-type triterpene, 20( R),24( E)-3-oxo-9 beta-lanosta-7,24-dien-26-oic acid ( 6), were isolated from the methanol extract of the Kadsura coccinea roots. Their structures were elucidated on the basis of spectroscopic evidence including ESI-MS, HR-EI-MS, 1D and 2D NMR. The protective effects of these compounds were evaluated in primary cultured rat hepatocytes intoxicated with 1.2 mM T-butyl hydroperoxide. Compounds 1, 3, and 5 showed protective effects with ED (50) values of 135.7, 26.1, and 79.3 microM, respectively.

Kadsutherin D, a new dibenzocyclooctadiene lignan from Kadsura species.[Pubmed:19023792]

Nat Prod Res. 2008;22(15):1344-9.

A new dibenzocyclooctadiene lignan, kadsutherin D (1), together with 12 known lignans, kadsurin (2), heteroclitin C (3), interiotherin C (4), schisanlignone A (5), Binankadsurin A (6), angeloyl Binankadsurin A (7), gomisin U (8), heteroclitin D (9), interiorin (10), schiarisanrin C (11), heteroclitin G (12) and meso-dihydroguaiaretic acid (13) were isolated from the stems of Kadsura species. Their structures were elucidated by spectroscopic methods including 2D-NMR techniques.

Lignans from Kadsura angustifolia.[Pubmed:18278869]

J Nat Prod. 2008 Apr;71(4):558-63.

Phytochemical investigation of Kadsura angustifolia led to the isolation and identification of 26 lignans and two triterpenoids, including 11 new lignans named kadangustins A-K ( 1- 11). The structures and stereochemistry of 1- 11 were elucidated by analysis of spectroscopic data. Except for 11 and 20, all the lignans were evaluated for their inhibitory activity against HIV-1. Binankadsurin A ( 19) showed anti-HIV activity with an EC 50 value of 3.86 microM.

Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease.[Pubmed:16394567]

Chem Pharm Bull (Tokyo). 2006 Jan;54(1):129-32.

Three new lignans, longipedunins A (1), B (2) and C (3), together with three known compounds, benzoyl-Binankadsurin A (4), acetyl-Binankadsurin A (5) and schisanlactone A (6), were isolated from Kadsura longipedunculata. Their structures and stereochemistry were determined by spectral and single-crystal X-ray analyses. Compounds 1 and 6 showed appreciable inhibitory activity against HIV-1 protease with IC50 values of 50 and 20 microM, respectively.

Three New Dibenzocyclooctadiene Lignans from Kadsura longipedunculata.[Pubmed:17226144]

Planta Med. 1991 Apr;57(2):169-71.

Five dibenzocyclooctadiene lignans were isolated from the stems of KADSURA LONGIPEDUNCULATA collected in Guangxi province. Three of them are new compounds, named benzoyl-, isovaleroyl-, and isobutyroylBinankadsurin A. Binankadsurin A was isolated from nature for the first time. The absolute configuration of isovaleroyloxokadsurane, a spirobenzofuranoid lignan from K. COCCINEA, was confirmed by chemical correlation with isovaleroylBinankadsurin A.

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