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BCN1917/21956-47-8 |
Littorine
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Littorine is not converted directly to the alkaloid, and it is suggested that it is hydrolysed in vivo to tropine and phenyl-lactic acid, the latter undergoing rearrangement to tropic acid prior to esterification with tropine.[1]
There are short-term toxic effects of 1-naphthol on the...
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BCN2308/20958-18-3 |
Dihydroisotanshinone I
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Dihydrotanshinone I and cryptotanshinone, constituents of a medicinal plant, Salvia miltiorrhiza Bunge, have antibacterial activity against a broad range of Gram positive bacteria, they have non-selectively inhibition against DNA, RNA, and protein syntheses in B. subtilis, suggest th...
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BCN2336/22368-21-4 |
Eupatilin
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Eupatilinthe has anti-proliferative effect in MCF10A- ras cells, is associated with its blockade of cell cycle progression which appears to be attributable in part to inhibition of ERK1/2 activation.[1]
Eupatilin attenuates bile acid-induced hepatocyte apoptosis by suppressing bile ...
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BCN2352/17910-09-7 |
Curzerene
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Curzerene is a sesquiterpene and component used in oriental medicine, was originally isolated from the traditional Chinese herbal medicine Curcuma rhizomes, it could induce the downregulation of GSTA1 protein and mRNA expressions in SPC-A1 cells, might be used as an anti-lung adenoc...
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BCN2358/465-11-2 |
Gamabufotalin
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Gamabufotalin(CS-6), a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells, suggests that CS-6 exhibits potential use in the treatment of COX-2-mediated diseases such as lung cancer.[1]
Gamabufotalin...
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BCN2359/472-26-4 |
Telocinobufagin
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Telocinobufagin (TCB), a bufadienolide extracted from Bufo paracnemis parotoid glands, shows a reversible local anesthetic action, similar to BUPI, however, without cardiac toxicity in vitro. [1]
Telocinobufagin is a novel endogenous digitalis, exhibits elevated plasma levels in patie...
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BCN2378/495-31-8 |
Nodakenin
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Nodakenin, a coumarin isolated from the roots of Angelica biserrata (Shan et Yuan) Yuan etShan, possesses neuroprotective, antiaggregatory, antibacterial, and memory
-enhancing effects; down-regulates the expression of the proinflammatory iNOS, COX-2, TNF-α, IL-6, and IL-1β genes in...
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BCN2394/509-20-6 |
Aconine
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Aconine can inhibit RANKL-induced osteoclast differentiation in RAW264.7 cells by suppressing NF-κB and NFATc1 activation and DC-STAMP expression.[1]
Aconine has GW26-e4470 effect on the expression of Sirt-1 and eNOS system in EAhy926 cell injured by Homocysteine.[2]
Aconine can atte...
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