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BCN5159/27013-91-8 |
alpha-Hederin
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Alpha-hederin as a pro-drug, has cytotoxic and apoptotic/necrotic effects in a dose- and time-dependent manner on on four human cancer cell lines [A549 (lung carcinoma), HEp-2 (larynx epidermoid carcinoma), HT-29 (colon adenocarcinoma) and MIA PaCa-2 (pancreas carcinoma)] .[1]
Alpha-h...
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BCN5166/2761-77-5 |
Communic acid
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Brown pine leaf extract (BPLE) and trans-communic acid (TCA) elicit reductions in UVB-induced MMP-1 mRNA expression and activator protein-1 (AP-1) transactivation by reducing DNA binding activity of phospho-c-Jun, c-fos and Fra-1, they also inhibit UVB-induced Akt phosphorylation, bu...
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BCN5171/27741-01-1 |
Geniposidic acid
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Geniposidic acid, one of the main active ingredients in Gardenia jasminoides J. Ellis (Rubiaceae), has anti-atherosclerotic effects, can protect vascular endothelium and reverse plaque formation in an atherosclerotic model.[1]
Geniposidic acid and geniposide have antitumor effect...
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BCN5206/29883-15-6 |
Amygdalin
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Amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax,suggests it may offer a valuable option for the treatment of prostate cancers.[1]
Amygdalin suppresses the prostaglan...
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BCN5237/31712-49-9 |
Hesperetin 7-O-glucoside
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Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium , because of the capacity of glucosyltransferase from cell-free extracts of C. aurantium tissues to glucosylate naringenin and hesperetin .[1]...
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BCN5241/32383-76-9 |
Medicarpin
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Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERβ, promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in addition, given its excellent oral bioavailability, it can be poten...
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BCN5277/34425-25-7 |
Lyoniside
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Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes,
they effectively kill L. donovani amastigotes inside macrophages in vitro , demonstrate strong anti-leishmanial efficacies in BALB/c mice model of leishmaniasis, suggests that these two compoun...
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BCN5285/3486-67-7 |
Palmatine
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Palmatine , a protoberberine alkaloid, is present in preparations from medicinal plants such as Coptis chinensis and Corydalis yanhusuo, palmatine activates the AhR-CYP1A pathway in HepG2 monolayer, while the potential for CYP1A induction is irrelevant in cell systems which are close...
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