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BCN4988/81740-07-0 |
Praeruptorin B
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Praeruptorin B has significant P-glycoprotein (Pgp)-inhibition activity.[1]
Praeruptorins B and A have LC 50 values of 34.5 and121.2 ug/ml, respectively, in Artemia salina test . [2]...
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BCN4991/72463-77-5 |
Praeruptorin C
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Praeruptorin C (Pra-C), one of the principal bioactive components derived from the root of Peucedanum praeruptorum Dunn, has been widely used as an antioxidant and a calcium antagonist to treat diseases, Pra-C partially also protects cortical neurons by inhibiting the expression of G...
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BCN5000/19573-01-4 |
(+-)-Byakangelicin
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Byakangelicin is found in extracts of the root of Angelica dahurica, used in Korea and China as a traditional medicine to treat colds, headache and toothache, it can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones, it induces cytochrome P450 ...
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BCN5005/20183-47-5 |
Tenuifolin
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Tenuifolin is an effective compound from tenuigenin, is commonly used in traditional Chinese herbal medicine for memory loss, has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.[1]
Tenuifolin...
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BCN5023/13476-25-0 |
Linderane
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Linderane (LDR), a furan-containing sesquiterpenoid, is found in Lindera aggregata (Sims) Kosterm, a common traditional Chinese herbal medicine, was characterized as a mechanism-based inactivator of CYP2C9.[1]...
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BCN5094/2415-24-9 |
Catalpol
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Catalpol, an iridoid glucoside, has been reported to inhibit apoptosis of neuron and endothelial cells; the pretreatment of H9c2 cells with catalpol can be against H 2 O 2 -induced apoptosis, and the protective effect of catalpol involves the mitochondrial-dependent caspase pathway an...
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BCN5103/24480-45-3 |
Bryonolic acid
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Bryonolic acid(BA), isolated in high yield from transformed hairy root cultures of Trichosanthes kirilowii var. Japonica, it exhibits cytotoxic activity to various tumor cells in vitro, independent of cell type. [1]
Bryonolic acid can induce a marked increase in the expression of a ...
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BCN5150/26791-73-1 |
Xanthatin
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Xanthatin, a natural sesquiterpene lactone, has significant antitumor activity against a variety of cancer cells; it displays significant antitumor effects through cell cycle arrest and apoptosis induction in A549 cells, these effects are associated with intrinsic apoptosis pathway an...
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