InChI=1S/C15H16O4/c1-8-4-3-5-15-13(19-15)12(18-14(15)16)11-9(2)7-17-10(11)6-8/h4,7,12-13H,3,5-6H2,1-2H3/b8-4+/t12-,13-,15-/m0/s1
Linderane (LDR), a furan-containing sesquiterpenoid, is found in Lindera aggregata (Sims) Kosterm, a common traditional Chinese herbal medicine, was characterized as a mechanism-based inactivator of CYP2C9.[1]
[1] Wang H, Wang K, Mao X, et al. Xenobiotica, 2015, 45(12):1037-46.
[2] Shi-Hui L I, Guang-Jun H E, Ying L U, et al. Guide of China Medicine, 2015(6):32-3.
