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BCN4606/642-18-2 |
Alstonine
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Alstonine has antipsychotic-like effects, can prevent MK801-induced working memory deficit and is also effective in counteracting MK801-induced hyperlocomotion and social interaction deficit , indicating its potential benefit for cognitive deficits now seen as a core symptom in the di...
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BCN4734/111035-65-5 |
Annonacin
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Annonacin, a natural lipophilic mitochondrial complex I inhibitor, can increase phosphorylation of tau in the brain of FTDP-17 transgenic mice, and induce nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe.[1,2]
Annonacin in Asim...
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BCN4865/19716-26-8 |
Stigmasterol glucoside
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Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.[1,2]...
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BCN4897/2061-64-5 |
Ergosterol peroxide
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Ergosterol peroxide(EPO) is a major antitumor sterol produced by edible or medicinal mushrooms, the bacterial metabolites of EPO play a significant role in its cytotoxic activity against human colorectal cancer cells. [1]
Ergosterol peroxide can exert antitumor activity in multiple...
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BCN4950/55466-05-2 |
Jujuboside B
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Jujuboside B is one of the saponins isolated from the seeds of Zizyphus jujuba var, has
antitumor activity and the underlying mechanism via induction of apoptosis and autophagy.[1]
Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, a...
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BCN4952/80681-45-4 |
Prim-O-glucosylcimifugin
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Prim-O-glucosylcimifugin is main medicinal component of the traditional Chinese drug Saposhnikovia divaricata, can increase concentrations of astragaloside IV and atractylenolide I in the serum, when they were given together.[1]
Prim-O-glucosylcimifugin has inhibition on NO productio...
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BCN4981/6902-91-6 |
Germacrone
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Germacrone, a natural product isolated from Rhizoma curcuma, can inhibit the proliferation of breast cancer cell lines by inducing cell cycle arrest and apoptosis through mitochondria-mediated caspase pathway. [1]
Germacrone moderately inhibits CYP2B6 and CYP3A4 activities in vitro, w...
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BCN4982/58479-68-8 |
Platycodin D
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Platycodon D (PD) and D3 (PD3) isolated from Platycodon grandiflorum has been previously reported to show anti-inflammatory activities in rats, PD may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA, suggest a dichotomous regulation of these important proinflammatory...
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