Alstonine has antipsychotic-like effects, can prevent MK801-induced working memory deficit and is also effective in counteracting MK801-induced hyperlocomotion and social interaction deficit , indicating its potential benefit for cognitive deficits now seen as a core symptom in the disease; 5-HT 2A/C receptors are central to the antipsychotic-like effects of alstonine, consistently seen in mouse models relevant to the three dimensions of schizophrenia symptoms.[1]
Alstonine is a potential fluorescent marker for tiny tumor detection and imaging.[2]
[1] Linck V M, Bessa M M, Herrmann A P, et al. Prog Neuro-Psychoph, 2012, 36(1):29-33.
[2] Vodinh T. Proc Spie, 1997, 2976:332-40.
[3] Huang P, Li W J, He B T. Chinese journal of experimental formulas of Chinese medicine, 2014, 20 (1) : 66-9.
